Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ES969_RS06335 Genome accession   NZ_CP035402
Coordinates   1210455..1211111 (+) Length   218 a.a.
NCBI ID   WP_014479448.1    Uniprot ID   A0A165B643
Organism   Bacillus subtilis strain SRCM103576     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1205455..1216111
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES969_RS06305 (ES969_06305) oppF 1205919..1206836 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  ES969_RS06310 (ES969_06310) yjbB 1206943..1208160 (+) 1218 WP_080478438.1 MFS transporter -
  ES969_RS06315 (ES969_06315) yjbC 1208325..1208903 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  ES969_RS06320 (ES969_06320) spx 1209084..1209479 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  ES969_RS06325 (ES969_06325) yjbE 1209522..1210178 (-) 657 WP_003232944.1 TerC family protein -
  ES969_RS06330 (ES969_06330) - 1210348..1210488 (+) 141 WP_119122854.1 hypothetical protein -
  ES969_RS06335 (ES969_06335) mecA 1210455..1211111 (+) 657 WP_014479448.1 adaptor protein MecA Regulator
  ES969_RS06340 (ES969_06340) - 1211106..1211228 (-) 123 WP_003245684.1 hypothetical protein -
  ES969_RS06345 (ES969_06345) coiA 1211272..1212423 (+) 1152 WP_014479449.1 competence protein CoiA Machinery gene
  ES969_RS06350 (ES969_06350) pepF 1212653..1214482 (+) 1830 WP_173401378.1 oligoendopeptidase F -
  ES969_RS06355 (ES969_06355) - 1214520..1214687 (-) 168 WP_003244944.1 hypothetical protein -
  ES969_RS06365 (ES969_06365) spxH 1215002..1215901 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25733.66 Da        Isoelectric Point: 4.1174

>NTDB_id=340242 ES969_RS06335 WP_014479448.1 1210455..1211111(+) (mecA) [Bacillus subtilis strain SRCM103576]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALEAIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=340242 ES969_RS06335 WP_014479448.1 1210455..1211111(+) (mecA) [Bacillus subtilis strain SRCM103576]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTATTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAGCGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A165B643

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.541

100

0.995

Multiple sequence alignment