Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ES968_RS06290 Genome accession   NZ_CP035395
Coordinates   1223482..1224138 (+) Length   218 a.a.
NCBI ID   WP_003245194.1    Uniprot ID   A0AAE2VF25
Organism   Bacillus subtilis strain SRCM103697     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1218482..1229138
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES968_RS06260 (ES968_06260) oppF 1218946..1219863 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  ES968_RS06265 (ES968_06265) yjbB 1219971..1221188 (+) 1218 WP_095010820.1 MFS transporter -
  ES968_RS06270 (ES968_06270) yjbC 1221352..1221930 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  ES968_RS06275 (ES968_06275) spx 1222111..1222506 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  ES968_RS06280 (ES968_06280) yjbE 1222549..1223205 (-) 657 WP_014479447.1 TerC family protein -
  ES968_RS06285 (ES968_06285) - 1223375..1223515 (+) 141 WP_119122854.1 hypothetical protein -
  ES968_RS06290 (ES968_06290) mecA 1223482..1224138 (+) 657 WP_003245194.1 adaptor protein MecA Regulator
  ES968_RS06295 (ES968_06295) - 1224133..1224255 (-) 123 WP_003245684.1 hypothetical protein -
  ES968_RS06300 (ES968_06300) coiA 1224299..1225450 (+) 1152 WP_046380934.1 competence protein CoiA Machinery gene
  ES968_RS06305 (ES968_06305) pepF 1225680..1227509 (+) 1830 WP_173401378.1 oligoendopeptidase F -
  ES968_RS06310 (ES968_06310) - 1227547..1227714 (-) 168 WP_003244944.1 hypothetical protein -
  ES968_RS06320 (ES968_06320) spxH 1228029..1228928 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25763.69 Da        Isoelectric Point: 4.1174

>NTDB_id=339846 ES968_RS06290 WP_003245194.1 1223482..1224138(+) (mecA) [Bacillus subtilis strain SRCM103697]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=339846 ES968_RS06290 WP_003245194.1 1223482..1224138(+) (mecA) [Bacillus subtilis strain SRCM103697]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

100

100

1

Multiple sequence alignment