Detailed information NTG0339793

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: ES967_RS12810
• Genome accession: NZ_CP035394
• Coordinates: 2482983..2485313 (-)
• Length: 776 a.a.
• NCBI ID: WP_069704087.1
• Uniprot ID: -
• Organism: Bacillus subtilis strain SRCM103696
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2477983..2490313

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES967_RS12775 (ES967_12775)	yqxA	2478321..2478659 (-)	339	WP_014477382.1	YqxA family protein	-
ES967_RS12780 (ES967_12780)	spoIIP	2478676..2479881 (-)	1206	WP_038429323.1	spore autolysin SpoIIP	-
ES967_RS12785 (ES967_12785)	gpr	2479944..2481050 (-)	1107	WP_014480309.1	GPR endopeptidase	-
ES967_RS12790 (ES967_12790)	rpsT	2481254..2481520 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
ES967_RS12795 (ES967_12795)	holA	2481535..2482578 (-)	1044	WP_015714286.1	DNA polymerase III subunit delta	-
ES967_RS12800 (ES967_12800)	-	2482618..2482767 (-)	150	WP_003229985.1	hypothetical protein	-
ES967_RS12805 (ES967_12805)	yqzM	2482808..2482942 (+)	135	WP_003229983.1	YqzM family protein	-
ES967_RS12810 (ES967_12810)	comEC	2482983..2485313 (-)	2331	WP_069704087.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ES967_RS12815 (ES967_12815)	comEB	2485317..2485886 (-)	570	WP_003229978.1	ComE operon protein 2	-
ES967_RS12820 (ES967_12820)	comEA	2485953..2486570 (-)	618	WP_004398514.1	competence protein ComEA	Machinery gene
ES967_RS12825 (ES967_12825)	comER	2486654..2487475 (+)	822	WP_014480313.1	late competence protein ComER	-
ES967_RS12830 (ES967_12830)	yqeM	2487541..2488284 (-)	744	WP_003229973.1	class I SAM-dependent methyltransferase	-
ES967_RS12835 (ES967_12835)	rsfS	2488281..2488637 (-)	357	WP_014480315.1	ribosome silencing factor	-
ES967_RS12840 (ES967_12840)	yqeK	2488655..2489215 (-)	561	WP_014480316.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
ES967_RS12845 (ES967_12845)	nadD	2489205..2489774 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
ES967_RS12850 (ES967_12850)	yhbY	2489786..2490076 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86753.40 Da
• Isoelectric Point: 7.3649

>NTDB_id=339793 ES967_RS12810 WP_069704087.1 2482983..2485313(-) (comEC) [Bacillus subtilis strain SRCM103696]
MRNSRLLLPMAAASATAGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDTIPKIDGDRMSMMVETPDKEKWAAAYRIQSAGEKEQLLYIEPGMSCELTGTLEEPKHATVPGAFDYNEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHIISFTNSLLPPDSAGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIMIRLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMSGVYLAGSLVKWRVHSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFQQVKTSLGQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWTNRLITKIADVDVFTIMIAHPAPVLLFLFTVTIILLLMAIEKRSLSQLMVTGG
ICCTVLFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKVLIPFLTAKG
IKQLDALILTHADQDHIGEAETLLKHHKVKRLVIPKGFVSEPKDEKVLQTAREEGVTIEEVKRGDVLQIKDLQFHVLSPE
TPDPASKNNSSLVLWMETGVLSWILTGDLEKEGEQEVMDVFPNIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKN
NRYHHPHQKVLQLLQRHSIRVLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=339793 ES967_RS12810 WP_069704087.1 2482983..2485313(-) (comEC) [Bacillus subtilis strain SRCM103696]
ATGCGTAATTCGCGCTTATTATTGCCTATGGCGGCAGCTTCGGCAACGGCTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATTTTAATCAAAACGAGGCACGCTTTTCTTATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACCTATCAATTC
AAGGCAGTGATTGACACTATTCCCAAAATTGACGGCGACCGTATGTCTATGATGGTTGAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCAGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACATTGGAAGAACCGAAACACGCAACTGTGCCGGGTGCATTTGATTATAACGAGTATCTCTATCGGCAGCATATT
CATTGGAACTACTCTGTCACGTCTATCCAAAACTGCAGCGAACCTGAAAATTTCAAGTACAAGGTGCTCAGTTTGAGAAA
ACATATCATATCATTCACAAACAGCCTTCTGCCTCCTGATTCGGCAGGGATTGTACAGGCACTTACAGTTGGTGACAGAT
TTTATGTGGAGGATGAAGTGCTTACCGCGTATCAAAAGCTTGGGGTTGTCCATCTCTTGGCAATATCAGGACTCCACGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATGATTCGCCTTGGTATAACTAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTCCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGTCTTGTCAAATGGCGTGTCCACTCTGCAACTGCAATTTGCCTTTCATACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCTGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCAGCA
GGTTAAAACCTCCTTGGGGCAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTCCTGTATCATT
TTCATCAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGCTGGTTTGATTTATTGATAAGCTG
GACCAATAGGTTAATCACAAAAATTGCAGATGTTGATGTGTTCACGATTATGATCGCACATCCTGCACCTGTTTTGCTTT
TTTTATTCACGGTCACGATCATCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGGTAACCGGCGGC
ATTTGCTGCACAGTGCTGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCATCAGCGGGGTCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGGTGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAACAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGACTCTGCTGAAGCATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAGGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGACAGCCAGAGAAG
AGGGAGTGACAATTGAAGAGGTGAAGCGAGGCGATGTATTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCTGAA
ACACCTGATCCGGCAAGCAAAAATAATTCCTCTCTCGTTCTGTGGATGGAGACGGGCGTTCTGAGCTGGATCTTGACGGG
TGATCTGGAAAAAGAAGGGGAACAGGAGGTGATGGACGTGTTTCCAAATATTAAAGCAGATGTCTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCATCCAACAGCTTCAGCCGAAAACGGCCATTATCTCAGCCGGGAAAAAC
AATCGGTACCATCATCCTCATCAAAAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGATCAAAA
CGGAACGATCCAATATAGATACAAAAACAGAGTTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (208-469)

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	98.325	100	0.983