Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   F3P13_RS10035 Genome accession   NZ_CP043946
Coordinates   2073137..2073793 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain AR202.2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2068137..2078793
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F3P13_RS10000 (F3P13_10000) dcyD 2069016..2070002 (+) 987 WP_039023114.1 D-cysteine desulfhydrase -
  F3P13_RS10005 (F3P13_10005) tcyL 2070017..2070685 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  F3P13_RS10010 (F3P13_10010) tcyN 2070682..2071434 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  F3P13_RS10015 (F3P13_10015) sdiA 2071664..2072386 (+) 723 WP_001154260.1 transcriptional regulator SdiA -
  F3P13_RS10020 (F3P13_10020) yecF 2072454..2072678 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  F3P13_RS10025 (F3P13_10025) yecU 2072665..2072841 (-) 177 WP_000590344.1 protein YecU -
  F3P13_RS26090 (F3P13_10030) - 2072879..2072995 (-) 117 WP_001302039.1 hypothetical protein -
  F3P13_RS10035 (F3P13_10035) letA 2073137..2073793 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  F3P13_RS10040 (F3P13_10040) uvrC 2073790..2075622 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  F3P13_RS10045 (F3P13_10045) pgsA 2075679..2076227 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  F3P13_RS10065 (F3P13_10065) yecA 2076876..2077541 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=339557 F3P13_RS10035 WP_000611328.1 2073137..2073793(+) (letA) [Escherichia coli strain AR202.2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=339557 F3P13_RS10035 WP_000611328.1 2073137..2073793(+) (letA) [Escherichia coli strain AR202.2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482