Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   ESP48_RS07005 Genome accession   NZ_CP035306
Coordinates   1292942..1294261 (+) Length   439 a.a.
NCBI ID   WP_064355977.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain IDCC2201     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1287942..1299261
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ESP48_RS06980 (ESP48_06980) - 1288796..1289560 (+) 765 WP_002949740.1 ABC transporter ATP-binding protein -
  ESP48_RS06985 (ESP48_06985) - 1289560..1290270 (+) 711 WP_011680767.1 ABC transporter ATP-binding protein -
  ESP48_RS06990 (ESP48_06990) - 1290406..1291066 (+) 661 Protein_1290 CBS and ACT domain-containing protein -
  ESP48_RS06995 (ESP48_06995) cysK 1291233..1292159 (-) 927 WP_011680768.1 cysteine synthase A -
  ESP48_RS07000 (ESP48_07000) - 1292261..1292887 (-) 627 WP_011680769.1 YigZ family protein -
  ESP48_RS07005 (ESP48_07005) comFA/cflA 1292942..1294261 (+) 1320 WP_064355977.1 DEAD/DEAH box helicase Machinery gene
  ESP48_RS07010 (ESP48_07010) - 1294242..1294904 (+) 663 WP_011680771.1 ComF family protein -
  ESP48_RS07015 (ESP48_07015) hpf 1294983..1295531 (+) 549 WP_011680772.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50655.79 Da        Isoelectric Point: 9.7105

>NTDB_id=339194 ESP48_RS07005 WP_064355977.1 1292942..1294261(+) (comFA/cflA) [Streptococcus thermophilus strain IDCC2201]
MIPKEYYGRLFTKEQLPVDYLSEAVKLESMIKVDKKLRCKRCYSRIEEDWQLPNGQYYCRACIVFGRNQEGKELYYFPSE
KSEVDFHVLKWSGKLTPYQNEVSEKLLKTYKNQKHSLVHAVTGAGKTEMIYNIVAYVLENKNRVVIASPRVDVCRELFLR
MQKDFTCSISLLHADSEPYDGSPLVIATTHQLLKFYHSFDLIIVDEVDAFPFVGNVMLNHAVKQAKTETGRYIYLTATST
LALEEQVRLGAIEKHHLASRFHGNPLVLPRFFWQGRLQKSLTSEKLPRPLIHQIKKQRKSNFPLLIFFPNIALGEKFSIT
LKKYLPTENIAFVSSKSEERSTIVEKFRKKELTILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPER
PTGKLYFFHEGLSKSMLQCRKEINAMNKKGGFENEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=339194 ESP48_RS07005 WP_064355977.1 1292942..1294261(+) (comFA/cflA) [Streptococcus thermophilus strain IDCC2201]
ATGATACCTAAAGAATATTATGGACGACTATTTACGAAAGAACAGTTACCAGTGGATTATCTCTCAGAGGCTGTAAAATT
AGAAAGTATGATAAAGGTTGATAAAAAACTTAGATGTAAAAGATGTTATAGTCGAATAGAGGAAGATTGGCAATTACCGA
ATGGTCAGTATTATTGTAGAGCGTGTATTGTCTTTGGTCGAAACCAAGAAGGAAAAGAACTCTATTACTTTCCCTCAGAA
AAATCAGAAGTAGATTTTCATGTCTTGAAATGGTCAGGAAAACTGACTCCTTATCAAAATGAGGTCTCGGAAAAGCTTTT
AAAGACTTATAAAAATCAAAAACACAGTCTTGTTCATGCAGTGACTGGTGCTGGCAAGACAGAGATGATTTATAATATTG
TTGCCTATGTTCTTGAAAATAAAAATCGTGTCGTCATCGCAAGTCCCCGAGTTGATGTTTGTCGAGAATTGTTTCTACGC
ATGCAGAAAGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGATAGTGAACCATATGATGGTAGTCCGCTCGTTATAGC
TACCACTCATCAATTACTAAAATTTTATCATAGCTTTGACTTGATTATTGTTGACGAAGTTGATGCCTTTCCATTTGTAG
GGAATGTCATGTTAAATCATGCTGTTAAACAGGCAAAGACGGAAACAGGCCGGTATATTTACTTGACAGCAACTTCTACA
TTAGCTTTAGAAGAGCAAGTGCGCCTTGGAGCTATAGAAAAGCATCACCTTGCTAGTCGTTTCCACGGAAATCCTCTAGT
CCTTCCTCGTTTCTTTTGGCAAGGAAGGTTACAAAAGTCGTTGACGAGCGAGAAGCTTCCAAGGCCTCTAATTCACCAGA
TTAAGAAGCAGCGTAAATCAAATTTTCCTCTATTAATCTTTTTCCCCAATATAGCATTAGGTGAAAAGTTTAGTATTACC
CTAAAAAAATATCTCCCTACTGAAAACATAGCCTTTGTTTCATCAAAAAGCGAGGAGCGTTCAACCATCGTAGAGAAATT
CCGAAAAAAAGAATTGACAATCTTAGTGACGACAACTATTCTCGAACGTGGTGTTACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATATACTAGTTCGAGTCTTATTCAGATTGGTGGTAGGGTGGGGCGTTCGCCCGAGAGA
CCTACAGGGAAACTCTATTTCTTTCATGAAGGATTATCTAAATCAATGTTGCAATGTCGGAAAGAAATAAATGCAATGAA
TAAAAAAGGAGGGTTTGAAAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

Type III restriction enzyme, res subunit (ResIII)

(94-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

55.22

98.178

0.542
  comFA/cflA Streptococcus pneumoniae D39

55.22

98.178

0.542
  comFA/cflA Streptococcus pneumoniae R6

55.22

98.178

0.542
  comFA/cflA Streptococcus pneumoniae TIGR4

55.22

98.178

0.542
  comFA/cflA Streptococcus mitis NCTC 12261

54.884

97.95

0.538
  comFA/cflA Streptococcus mitis SK321

54.186

97.95

0.531
  comFA Lactococcus lactis subsp. cremoris KW2

45.476

95.672

0.435
  comFA Latilactobacillus sakei subsp. sakei 23K

36.782

99.089

0.364

Multiple sequence alignment