Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   F1719_RS08420 Genome accession   NZ_CP043852
Coordinates   1595912..1596568 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli ATCC 8739     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1590912..1601568
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F1719_RS23720 (F1719_08600) - 1590999..1591079 (+) 81 Protein_1549 hypothetical protein -
  F1719_RS08385 (F1719_08605) - 1591076..1592227 (+) 1152 WP_203448723.1 IS30-like element IS30 family transposase -
  F1719_RS08390 (F1719_08610) - 1592240..1592542 (-) 303 Protein_1551 transposase -
  F1719_RS23725 (F1719_08615) - 1592577..1592780 (+) 204 Protein_1552 hypothetical protein -
  F1719_RS08410 (F1719_08635) pgsA 1593478..1594026 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  F1719_RS08415 (F1719_08640) uvrC 1594083..1595915 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  F1719_RS08420 (F1719_08645) letA 1595912..1596568 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  F1719_RS23990 - 1596710..1596781 (+) 72 Protein_1556 transcriptional regulator -
  F1719_RS08425 (F1719_08650) yecU 1596864..1597040 (+) 177 WP_000590347.1 protein YecU -
  F1719_RS08430 (F1719_08655) yecF 1597027..1597251 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  F1719_RS08435 (F1719_08660) sdiA 1597319..1598041 (-) 723 WP_001152713.1 transcriptional regulator SdiA -
  F1719_RS08440 (F1719_08665) tcyN 1598271..1599023 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  F1719_RS08445 (F1719_08670) tcyL 1599020..1599688 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  F1719_RS08450 (F1719_08675) dcyD 1599703..1600689 (-) 987 WP_001128208.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=339148 F1719_RS08420 WP_000611328.1 1595912..1596568(-) (letA) [Escherichia coli ATCC 8739]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=339148 F1719_RS08420 WP_000611328.1 1595912..1596568(-) (letA) [Escherichia coli ATCC 8739]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCAACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGTCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482