Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   EQ030_RS08855 Genome accession   NZ_CP035294
Coordinates   1825696..1826262 (-) Length   188 a.a.
NCBI ID   WP_011303464.1    Uniprot ID   Q49WF9
Organism   Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 = NCTC 7292 strain ATCC 15305     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1820696..1831262
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQ030_RS08820 (EQ030_08825) - 1820914..1822266 (-) 1353 WP_011303459.1 isochorismate synthase -
  EQ030_RS08825 (EQ030_08830) - 1822455..1823393 (+) 939 WP_011303460.1 1,4-dihydroxy-2-naphthoate polyprenyltransferase -
  EQ030_RS08830 (EQ030_08835) - 1823504..1824061 (-) 558 WP_011303461.1 GNAT family N-acetyltransferase -
  EQ030_RS08835 (EQ030_08840) - 1824229..1824441 (+) 213 WP_011303462.1 TM2 domain-containing protein -
  EQ030_RS13025 - 1824561..1824650 (+) 90 WP_011303463.1 SAR1012 family small protein -
  EQ030_RS08840 (EQ030_08845) - 1824737..1825165 (-) 429 WP_002483731.1 organic hydroperoxide resistance protein -
  EQ030_RS08855 (EQ030_08860) comK/comK1 1825696..1826262 (-) 567 WP_011303464.1 competence protein ComK Regulator
  EQ030_RS08860 (EQ030_08865) - 1826514..1826732 (+) 219 WP_011303465.1 IDEAL domain-containing protein -
  EQ030_RS08865 (EQ030_08870) - 1826814..1827803 (-) 990 WP_002483734.1 lipoate--protein ligase -
  EQ030_RS08870 (EQ030_08875) - 1828004..1828189 (+) 186 WP_002483735.1 DUF2187 family protein -
  EQ030_RS08875 (EQ030_08880) - 1828195..1828797 (+) 603 WP_002483736.1 CPBP family glutamic-type intramembrane protease -
  EQ030_RS08880 (EQ030_08885) - 1829388..1830896 (-) 1509 WP_011303467.1 bifunctional UDP-sugar hydrolase/5'-nucleotidase -

Sequence

Protein


Download         Length: 188 a.a.        Molecular weight: 22095.50 Da        Isoelectric Point: 9.5132

>NTDB_id=339029 EQ030_RS08855 WP_011303464.1 1825696..1826262(-) (comK/comK1) [Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 = NCTC 7292 strain ATCC 15305]
MIQPYIIKKGDMVLQPCSLSTGKYEGSYLLKYKDDSKVLKERVPKIIDRSCRFYGSSYNFKKEDTMRITGISSKPPILFT
PLFPTYFFPTHSDRKEENTWINIHYVHQIKPLKEKKCKVTFVDNQTIVANISAHSMHHQYLNGIYYYYMMDRAARVATFD
PESPIDYTKPQLNIYEALAKYSLFENKS

Nucleotide


Download         Length: 567 bp        

>NTDB_id=339029 EQ030_RS08855 WP_011303464.1 1825696..1826262(-) (comK/comK1) [Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 = NCTC 7292 strain ATCC 15305]
ATGATTCAACCCTATATCATTAAAAAAGGGGATATGGTTTTACAACCATGCAGTTTATCAACTGGTAAGTATGAAGGTAG
TTATCTTTTAAAGTATAAGGATGACAGCAAAGTTCTAAAAGAACGTGTTCCAAAGATTATTGATCGATCGTGTAGATTTT
ATGGTAGTAGTTATAATTTTAAGAAAGAAGATACGATGAGAATTACTGGCATAAGCAGTAAACCCCCAATTTTATTTACT
CCACTTTTTCCTACTTATTTTTTCCCAACGCACTCTGATAGAAAAGAAGAAAATACTTGGATTAATATTCATTATGTTCA
CCAAATCAAACCACTAAAAGAAAAGAAATGTAAAGTGACATTTGTAGATAATCAAACAATTGTAGCTAACATTTCAGCAC
ATAGCATGCATCATCAATACCTAAATGGTATTTATTATTACTATATGATGGATAGGGCAGCAAGAGTTGCTACCTTTGAT
CCAGAATCTCCTATTGATTATACAAAACCTCAATTAAATATTTATGAAGCATTAGCAAAATATTCATTATTTGAAAATAA
ATCATAG

Domains

Predicted by InterproScan.

ComK protein (ComK)

(4-152)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q49WF9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

54.891

97.872

0.537
  comK/comK1 Staphylococcus aureus N315

54.891

97.872

0.537

Multiple sequence alignment