Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   EQW00_RS08000 Genome accession   NZ_CP035288
Coordinates   1652245..1653117 (-) Length   290 a.a.
NCBI ID   WP_001829468.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain ATCC 14990     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1613785..1684598 1652245..1653117 within 0


Gene organization within MGE regions


Location: 1613785..1684598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQW00_RS07855 (EQW00_07860) - 1614825..1616096 (-) 1272 WP_002439538.1 pitrilysin family protein -
  EQW00_RS07860 (EQW00_07865) - 1616127..1616840 (-) 714 WP_002439536.1 GntR family transcriptional regulator -
  EQW00_RS07865 (EQW00_07870) - 1616843..1619236 (-) 2394 WP_002439534.1 DNA translocase FtsK -
  EQW00_RS07870 (EQW00_07875) - 1619502..1621175 (-) 1674 WP_002457357.1 ribonuclease J -
  EQW00_RS07875 (EQW00_07880) pnp 1621543..1623648 (-) 2106 WP_001832554.1 polyribonucleotide nucleotidyltransferase -
  EQW00_RS07880 (EQW00_07885) rpsO 1623780..1624049 (-) 270 WP_002439528.1 30S ribosomal protein S15 -
  EQW00_RS07885 (EQW00_07890) - 1624169..1625140 (-) 972 WP_001832563.1 bifunctional riboflavin kinase/FAD synthetase -
  EQW00_RS07890 (EQW00_07895) truB 1625156..1626073 (-) 918 WP_002456563.1 tRNA pseudouridine(55) synthase TruB -
  EQW00_RS07895 (EQW00_07900) rbfA 1626211..1626561 (-) 351 WP_001829509.1 30S ribosome-binding factor RbfA -
  EQW00_RS07900 (EQW00_07905) infB 1626864..1629026 (-) 2163 WP_002468903.1 translation initiation factor IF-2 -
  EQW00_RS07905 (EQW00_07910) - 1629031..1629348 (-) 318 WP_002439520.1 YlxQ family RNA-binding protein -
  EQW00_RS07910 (EQW00_07915) - 1629348..1629632 (-) 285 WP_001829465.1 YlxR family protein -
  EQW00_RS07915 (EQW00_07920) nusA 1629650..1630873 (-) 1224 WP_002456565.1 transcription termination factor NusA -
  EQW00_RS07920 (EQW00_07925) rimP 1630894..1631361 (-) 468 WP_002439519.1 ribosome maturation factor RimP -
  EQW00_RS07925 (EQW00_07930) - 1631540..1635850 (-) 4311 WP_002456566.1 PolC-type DNA polymerase III -
  EQW00_RS07930 (EQW00_07935) - 1636100..1637803 (-) 1704 WP_001829513.1 proline--tRNA ligase -
  EQW00_RS07935 (EQW00_07940) rseP 1637822..1639108 (-) 1287 WP_001829501.1 RIP metalloprotease RseP -
  EQW00_RS07940 (EQW00_07945) - 1639342..1640124 (-) 783 WP_001829499.1 phosphatidate cytidylyltransferase -
  EQW00_RS07945 (EQW00_07950) - 1640128..1640898 (-) 771 WP_001832561.1 isoprenyl transferase -
  EQW00_RS07950 (EQW00_07955) frr 1641119..1641673 (-) 555 WP_001829472.1 ribosome recycling factor -
  EQW00_RS07955 (EQW00_07960) pyrH 1641690..1642412 (-) 723 WP_002439511.1 UMP kinase -
  EQW00_RS07960 (EQW00_07965) tsf 1642553..1643431 (-) 879 WP_002439509.1 translation elongation factor Ts -
  EQW00_RS07965 (EQW00_07970) rpsB 1643583..1644371 (-) 789 WP_001832557.1 30S ribosomal protein S2 -
  EQW00_RS07970 (EQW00_07975) codY 1644734..1645504 (-) 771 WP_002439506.1 GTP-sensing pleiotropic transcriptional regulator CodY -
  EQW00_RS07975 (EQW00_07980) hslU 1645528..1646931 (-) 1404 WP_001829474.1 ATP-dependent protease ATPase subunit HslU -
  EQW00_RS07980 (EQW00_07985) hslV 1647000..1647542 (-) 543 WP_001829498.1 ATP-dependent protease subunit HslV -
  EQW00_RS07985 (EQW00_07990) xerC 1647546..1648436 (-) 891 WP_002456225.1 tyrosine recombinase XerC -
  EQW00_RS07990 (EQW00_07995) trmFO 1648661..1649968 (-) 1308 WP_001832560.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  EQW00_RS07995 (EQW00_08000) topA 1649993..1652062 (-) 2070 WP_002489763.1 type I DNA topoisomerase -
  EQW00_RS08000 (EQW00_08005) dprA 1652245..1653117 (-) 873 WP_001829468.1 DNA-processing protein DprA Machinery gene
  EQW00_RS12535 - 1653458..1653673 (-) 216 Protein_1495 IS200/IS605 family transposase -
  EQW00_RS08005 (EQW00_08010) sucD 1653923..1654831 (-) 909 WP_002446283.1 succinate--CoA ligase subunit alpha -
  EQW00_RS08010 (EQW00_08015) sucC 1654853..1656019 (-) 1167 WP_002439496.1 ADP-forming succinate--CoA ligase subunit beta -
  EQW00_RS08015 (EQW00_08020) - 1656127..1656897 (-) 771 WP_001829514.1 ribonuclease HII -
  EQW00_RS08020 (EQW00_08025) ylqF 1656902..1657765 (-) 864 WP_001829495.1 ribosome biogenesis GTPase YlqF -
  EQW00_RS12450 (EQW00_08030) - 1657786..1657935 (-) 150 WP_162154119.1 hypothetical protein -
  EQW00_RS08030 (EQW00_08035) - 1658094..1660694 (+) 2601 WP_002468914.1 YfhO family protein -
  EQW00_RS08035 (EQW00_08040) - 1660687..1663290 (+) 2604 WP_002470232.1 YfhO family protein -
  EQW00_RS08040 (EQW00_08045) rplS 1663820..1664170 (-) 351 WP_054828570.1 50S ribosomal protein L19 -
  EQW00_RS08045 (EQW00_08050) trmD 1664276..1665013 (-) 738 WP_001829466.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  EQW00_RS08050 (EQW00_08055) rimM 1665013..1665516 (-) 504 WP_001832559.1 ribosome maturation factor RimM -
  EQW00_RS08055 (EQW00_08060) rpsP 1665643..1665918 (-) 276 WP_002439483.1 30S ribosomal protein S16 -
  EQW00_RS08060 (EQW00_08065) ffh 1666164..1667531 (-) 1368 WP_001830113.1 signal recognition particle protein -
  EQW00_RS08065 (EQW00_08070) - 1667562..1667894 (-) 333 WP_002457379.1 putative DNA-binding protein -
  EQW00_RS08070 (EQW00_08075) ftsY 1667896..1669122 (-) 1227 WP_001830080.1 signal recognition particle-docking protein FtsY -
  EQW00_RS08075 (EQW00_08080) smc 1669119..1672688 (-) 3570 WP_002468549.1 chromosome segregation protein SMC -
  EQW00_RS08080 (EQW00_08085) rnc 1672815..1673552 (-) 738 WP_002470220.1 ribonuclease III -
  EQW00_RS08085 (EQW00_08090) - 1673667..1673900 (-) 234 WP_001830184.1 acyl carrier protein -
  EQW00_RS08090 (EQW00_08095) fabG 1674127..1674861 (-) 735 WP_001830161.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  EQW00_RS08095 (EQW00_08100) fabD 1674854..1675780 (-) 927 WP_002489765.1 ACP S-malonyltransferase -
  EQW00_RS08100 (EQW00_08105) plsX 1675782..1676759 (-) 978 WP_001830112.1 phosphate acyltransferase PlsX -
  EQW00_RS08105 (EQW00_08110) fapR 1676761..1677321 (-) 561 WP_001830099.1 transcription factor FapR -
  EQW00_RS08110 (EQW00_08115) recG 1677480..1679528 (-) 2049 WP_001830069.1 ATP-dependent DNA helicase RecG -
  EQW00_RS08115 (EQW00_08120) fakA 1679732..1681390 (-) 1659 WP_001830116.1 fatty acid kinase catalytic subunit FakA -
  EQW00_RS08120 (EQW00_08125) - 1681405..1681779 (-) 375 WP_001830156.1 Asp23/Gls24 family envelope stress response protein -
  EQW00_RS08125 (EQW00_08130) rpmB 1682137..1682325 (+) 189 WP_001830107.1 50S ribosomal protein L28 -
  EQW00_RS08130 (EQW00_08135) - 1682408..1683043 (-) 636 WP_001830164.1 thiamine diphosphokinase -
  EQW00_RS08135 (EQW00_08140) rpe 1683048..1683692 (-) 645 WP_001830173.1 ribulose-phosphate 3-epimerase -
  EQW00_RS08140 (EQW00_08145) rsgA 1683693..1684568 (-) 876 WP_001830137.1 ribosome small subunit-dependent GTPase A -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33726.62 Da        Isoelectric Point: 9.3618

>NTDB_id=338958 EQW00_RS08000 WP_001829468.1 1652245..1653117(-) (dprA) [Staphylococcus epidermidis strain ATCC 14990]
MIQHTMLKLYWANFTTAQLHHLTSTYPDFLSENVFHQHDMIKRWLTERNSERLWNKYERFKELKLMDIIKEMKKANVSFT
TYFDDNYPSLCKEMYDYPYVIFYKGNPQFFNHSHSLAVIGSRNATQYTSQSLNYLFPSFRQLNMAIVSGLARGADSVAHQ
TALKYLLPTIGVLGFGHCYHYPKATLNLRTKVERNGLVISEYPPFSPISKHKFPERNRLISGLSRGVLITEAEERSGSQI
TIDCALEQNRNVYVLPGSMFNKMTKGNLRRINEGAQVVIDESSILYDYLF

Nucleotide


Download         Length: 873 bp        

>NTDB_id=338958 EQW00_RS08000 WP_001829468.1 1652245..1653117(-) (dprA) [Staphylococcus epidermidis strain ATCC 14990]
TTGATACAACATACGATGTTAAAACTATATTGGGCAAATTTCACTACGGCACAACTTCATCATCTTACAAGTACATATCC
TGACTTTCTATCAGAAAACGTATTTCATCAACATGACATGATAAAAAGGTGGCTTACAGAGCGTAATTCTGAAAGGCTAT
GGAACAAATATGAACGTTTCAAAGAATTAAAGCTGATGGACATTATTAAAGAAATGAAAAAAGCAAATGTTAGTTTTACA
ACATACTTTGATGATAACTACCCTTCTCTTTGCAAAGAAATGTATGATTATCCTTATGTGATATTCTACAAAGGAAATCC
ACAGTTCTTTAATCATTCTCACTCTTTAGCTGTAATTGGCTCACGTAATGCCACACAATATACAAGTCAATCTTTAAACT
ATCTTTTTCCTTCATTTAGACAATTAAATATGGCGATTGTTTCTGGATTAGCGCGCGGTGCAGATAGTGTAGCACATCAA
ACCGCACTTAAATACCTATTACCAACTATTGGCGTACTTGGATTTGGCCATTGTTATCATTATCCTAAAGCAACCTTAAA
TTTAAGAACTAAAGTTGAAAGGAATGGCTTAGTGATAAGTGAATATCCACCATTTTCTCCTATAAGTAAGCATAAATTTC
CTGAAAGAAACAGGCTTATAAGTGGTCTGTCCAGAGGGGTACTTATAACTGAGGCTGAAGAAAGAAGTGGTAGTCAAATC
ACTATCGATTGTGCTTTAGAGCAAAATAGAAATGTTTATGTTCTACCTGGTTCAATGTTCAACAAAATGACTAAAGGTAA
TTTAAGAAGGATAAATGAAGGTGCTCAAGTTGTTATAGATGAAAGTAGTATATTATATGATTATCTATTTTAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus N315

56.944

99.31

0.566
  dprA Staphylococcus aureus MW2

56.944

99.31

0.566

Multiple sequence alignment