Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   EQH15_RS09150 Genome accession   NZ_CP035265
Coordinates   1776556..1777176 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain TVO_1901920     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1771556..1782176
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH15_RS09125 (EQH15_09600) recA 1771932..1773104 (-) 1173 WP_238102269.1 recombinase RecA Machinery gene
  EQH15_RS09130 (EQH15_09605) cinA 1773154..1774410 (-) 1257 WP_000642713.1 competence/damage-inducible protein A Machinery gene
  EQH15_RS09135 (EQH15_09610) brpA 1774495..1775511 (-) 1017 WP_000239284.1 biofilm formation/cell division transcriptional regulator BrpA -
  EQH15_RS09140 (EQH15_09615) - 1775519..1776037 (-) 519 WP_000455531.1 GNAT family N-acetyltransferase -
  EQH15_RS09145 (EQH15_09620) tsaE 1776027..1776470 (-) 444 WP_000275588.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  EQH15_RS09150 (EQH15_09625) comM 1776556..1777176 (-) 621 WP_000839908.1 hypothetical protein Regulator
  EQH15_RS09155 (EQH15_09635) - 1777559..1778422 (-) 864 WP_001093635.1 helix-turn-helix domain-containing protein -
  EQH15_RS10870 - 1778594..1778767 (+) 174 WP_033623142.1 PhrA family quorum-sensing system peptide -
  EQH15_RS09160 (EQH15_09640) - 1779082..1779378 (+) 297 WP_000911558.1 lactococcin 972 family bacteriocin -
  EQH15_RS09165 (EQH15_09645) - 1779481..1781496 (+) 2016 WP_000732381.1 bacteriocin-associated integral membrane family protein -
  EQH15_RS09170 (EQH15_09650) - 1781498..1782130 (+) 633 WP_000571413.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=338716 EQH15_RS09150 WP_000839908.1 1776556..1777176(-) (comM) [Streptococcus pneumoniae strain TVO_1901920]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=338716 EQH15_RS09150 WP_000839908.1 1776556..1777176(-) (comM) [Streptococcus pneumoniae strain TVO_1901920]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCTTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment