Detailed information
Bioinformatically predicted
Overview
| Name | clpX | Type | Regulator |
| Locus tag | EQH15_RS07345 | Genome accession | NZ_CP035265 |
| Coordinates | 1444255..1445487 (-) | Length | 410 a.a. |
| NCBI ID | WP_000106346.1 | Uniprot ID | A0A064C077 |
| Organism | Streptococcus pneumoniae strain TVO_1901920 | ||
| Function | require for competence development (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1400306..1454538 | 1444255..1445487 | within | 0 |
Gene organization within MGE regions
Location: 1400306..1454538
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EQH15_RS07025 (EQH15_07395) | lytA | 1400306..1401262 (-) | 957 | WP_000350493.1 | N-acetylmuramoyl-L-alanine amidase LytA | - |
| EQH15_RS07030 (EQH15_07400) | - | 1401266..1401598 (-) | 333 | WP_001186210.1 | phage holin | - |
| EQH15_RS07035 (EQH15_07405) | - | 1401602..1402018 (-) | 417 | WP_001165344.1 | phage holin family protein | - |
| EQH15_RS07040 (EQH15_07410) | - | 1402028..1402378 (-) | 351 | WP_000852248.1 | hypothetical protein | - |
| EQH15_RS07045 (EQH15_07415) | - | 1402381..1402584 (-) | 204 | WP_001091123.1 | hypothetical protein | - |
| EQH15_RS10975 (EQH15_07420) | - | 1402565..1402681 (-) | 117 | WP_001063633.1 | hypothetical protein | - |
| EQH15_RS07050 (EQH15_07425) | - | 1402678..1408293 (-) | 5616 | WP_061385712.1 | tail fiber domain-containing protein | - |
| EQH15_RS07055 (EQH15_07430) | - | 1408298..1408648 (-) | 351 | WP_000068021.1 | DUF6711 family protein | - |
| EQH15_RS07060 (EQH15_07435) | - | 1408657..1412310 (-) | 3654 | WP_061385713.1 | hypothetical protein | - |
| EQH15_RS07065 (EQH15_07440) | - | 1412297..1412647 (-) | 351 | WP_000478008.1 | hypothetical protein | - |
| EQH15_RS07070 (EQH15_07445) | - | 1412686..1413066 (-) | 381 | WP_001185635.1 | DUF6096 family protein | - |
| EQH15_RS07075 (EQH15_07450) | - | 1413071..1413484 (-) | 414 | WP_000880681.1 | phage tail tube protein | - |
| EQH15_RS07080 (EQH15_07455) | - | 1413487..1413855 (-) | 369 | WP_000608235.1 | hypothetical protein | - |
| EQH15_RS07085 (EQH15_07460) | - | 1413852..1414367 (-) | 516 | WP_000040512.1 | HK97-gp10 family putative phage morphogenesis protein | - |
| EQH15_RS07090 (EQH15_07465) | - | 1414342..1414680 (-) | 339 | WP_000478944.1 | hypothetical protein | - |
| EQH15_RS07095 (EQH15_07470) | - | 1414661..1414972 (-) | 312 | WP_000021225.1 | phage head-tail connector protein | - |
| EQH15_RS07100 (EQH15_07475) | - | 1414974..1415162 (-) | 189 | WP_000669345.1 | hypothetical protein | - |
| EQH15_RS07105 (EQH15_07480) | - | 1415172..1416197 (-) | 1026 | WP_000863389.1 | carbohydrate-binding protein | - |
| EQH15_RS07110 (EQH15_07485) | - | 1416220..1416744 (-) | 525 | WP_001288019.1 | DUF4355 domain-containing protein | - |
| EQH15_RS07115 (EQH15_07490) | - | 1416914..1417126 (-) | 213 | WP_000393349.1 | crAss001_48 related protein | - |
| EQH15_RS07120 (EQH15_07495) | - | 1417267..1417554 (-) | 288 | WP_001046058.1 | hypothetical protein | - |
| EQH15_RS07125 (EQH15_07500) | - | 1417597..1418010 (-) | 414 | WP_000565276.1 | HD domain-containing protein | - |
| EQH15_RS07130 (EQH15_07505) | - | 1418007..1418216 (-) | 210 | WP_000651747.1 | hypothetical protein | - |
| EQH15_RS07135 (EQH15_07510) | - | 1418218..1419855 (-) | 1638 | WP_000795722.1 | minor capsid protein | - |
| EQH15_RS07140 (EQH15_07515) | - | 1419764..1421233 (-) | 1470 | WP_078376601.1 | phage portal protein | - |
| EQH15_RS07145 (EQH15_07520) | - | 1421245..1422543 (-) | 1299 | WP_000084419.1 | PBSX family phage terminase large subunit | - |
| EQH15_RS07150 (EQH15_07525) | - | 1422521..1423033 (-) | 513 | WP_000863689.1 | terminase small subunit | - |
| EQH15_RS07160 (EQH15_07535) | - | 1424321..1424755 (-) | 435 | WP_001030239.1 | DUF1492 domain-containing protein | - |
| EQH15_RS07165 (EQH15_07540) | - | 1424829..1425200 (-) | 372 | WP_000801319.1 | hypothetical protein | - |
| EQH15_RS07170 (EQH15_07545) | - | 1425197..1425610 (-) | 414 | WP_000612396.1 | YopX family protein | - |
| EQH15_RS07175 (EQH15_07550) | - | 1425607..1426110 (-) | 504 | WP_001021771.1 | DUF1642 domain-containing protein | - |
| EQH15_RS07180 (EQH15_07555) | - | 1426112..1426426 (-) | 315 | WP_000391841.1 | hypothetical protein | - |
| EQH15_RS07185 (EQH15_07560) | - | 1426577..1426915 (-) | 339 | WP_000119453.1 | hypothetical protein | - |
| EQH15_RS07190 | - | 1426915..1427067 (-) | 153 | WP_000122746.1 | hypothetical protein | - |
| EQH15_RS07195 (EQH15_07565) | - | 1427361..1428704 (-) | 1344 | WP_000580027.1 | virulence-associated E family protein | - |
| EQH15_RS07200 (EQH15_07570) | - | 1428707..1429528 (-) | 822 | WP_001838318.1 | bifunctional DNA primase/polymerase | - |
| EQH15_RS07205 (EQH15_07575) | - | 1429701..1430207 (-) | 507 | WP_000054340.1 | hypothetical protein | - |
| EQH15_RS07210 (EQH15_07580) | - | 1430227..1431054 (-) | 828 | WP_238102256.1 | AAA family ATPase | - |
| EQH15_RS07215 (EQH15_07585) | - | 1431054..1431371 (-) | 318 | WP_001044592.1 | hypothetical protein | - |
| EQH15_RS07220 (EQH15_07590) | - | 1431390..1432583 (-) | 1194 | WP_000028862.1 | DEAD/DEAH box helicase family protein | - |
| EQH15_RS07225 (EQH15_07595) | - | 1432546..1433031 (-) | 486 | WP_000696056.1 | hypothetical protein | - |
| EQH15_RS07230 (EQH15_07600) | - | 1433031..1433390 (-) | 360 | WP_000422309.1 | hypothetical protein | - |
| EQH15_RS07235 (EQH15_07605) | - | 1433390..1433872 (-) | 483 | WP_000157808.1 | siphovirus Gp157 family protein | - |
| EQH15_RS07240 (EQH15_07610) | - | 1433865..1434587 (-) | 723 | WP_000544345.1 | HNH endonuclease signature motif containing protein | - |
| EQH15_RS07245 (EQH15_07615) | - | 1434601..1434831 (-) | 231 | WP_000252079.1 | hypothetical protein | - |
| EQH15_RS07250 (EQH15_07620) | - | 1434832..1435173 (-) | 342 | WP_000189401.1 | hypothetical protein | - |
| EQH15_RS07255 (EQH15_07625) | - | 1435185..1435376 (-) | 192 | WP_000970850.1 | hypothetical protein | - |
| EQH15_RS07260 (EQH15_07630) | - | 1435373..1435567 (-) | 195 | WP_001050924.1 | hypothetical protein | - |
| EQH15_RS07265 (EQH15_07635) | - | 1435564..1435836 (-) | 273 | WP_000388508.1 | hypothetical protein | - |
| EQH15_RS07270 | - | 1435916..1436059 (-) | 144 | WP_000389590.1 | hypothetical protein | - |
| EQH15_RS07275 (EQH15_07640) | - | 1436177..1436398 (+) | 222 | WP_000041096.1 | hypothetical protein | - |
| EQH15_RS07280 (EQH15_07645) | - | 1436512..1436703 (-) | 192 | WP_001112859.1 | DNA-binding protein | - |
| EQH15_RS07285 (EQH15_07650) | - | 1436768..1437007 (+) | 240 | WP_000142893.1 | hypothetical protein | - |
| EQH15_RS07290 (EQH15_07655) | - | 1437424..1437780 (+) | 357 | WP_000464162.1 | helix-turn-helix domain-containing protein | - |
| EQH15_RS07295 (EQH15_07660) | - | 1437782..1438204 (+) | 423 | WP_000181886.1 | hypothetical protein | - |
| EQH15_RS07300 (EQH15_07665) | - | 1438208..1438687 (+) | 480 | WP_001113481.1 | hypothetical protein | - |
| EQH15_RS10980 (EQH15_07670) | - | 1438708..1439087 (+) | 380 | Protein_1465 | ImmA/IrrE family metallo-endopeptidase | - |
| EQH15_RS07315 (EQH15_07675) | - | 1439229..1440356 (+) | 1128 | WP_000266847.1 | site-specific integrase | - |
| EQH15_RS07320 (EQH15_07680) | whiA | 1440444..1441355 (-) | 912 | WP_000011306.1 | DNA-binding protein WhiA | - |
| EQH15_RS07325 (EQH15_07685) | - | 1441352..1442329 (-) | 978 | WP_001231067.1 | YvcK family protein | - |
| EQH15_RS07330 (EQH15_07690) | rapZ | 1442326..1443216 (-) | 891 | WP_000163035.1 | RNase adapter RapZ | - |
| EQH15_RS07335 (EQH15_07695) | - | 1443268..1443648 (-) | 381 | WP_001140412.1 | RidA family protein | - |
| EQH15_RS07340 (EQH15_07700) | yihA | 1443659..1444246 (-) | 588 | WP_000422599.1 | ribosome biogenesis GTP-binding protein YihA/YsxC | - |
| EQH15_RS07345 (EQH15_07705) | clpX | 1444255..1445487 (-) | 1233 | WP_000106346.1 | ATP-dependent Clp protease ATP-binding subunit ClpX | Regulator |
| EQH15_RS07350 (EQH15_07710) | - | 1445519..1445689 (-) | 171 | WP_000442275.1 | hypothetical protein | - |
| EQH15_RS07355 (EQH15_07715) | - | 1445689..1446195 (-) | 507 | WP_000162486.1 | dihydrofolate reductase | - |
| EQH15_RS07360 (EQH15_07720) | - | 1446325..1446843 (-) | 519 | WP_000229874.1 | DNA starvation/stationary phase protection protein | - |
| EQH15_RS07365 (EQH15_07725) | lytC | 1447339..1448843 (-) | 1505 | Protein_1476 | choline binding-anchored murein hydrolase LytC | - |
| EQH15_RS07370 (EQH15_07730) | tpiA | 1448881..1449639 (-) | 759 | WP_000087897.1 | triose-phosphate isomerase | - |
| EQH15_RS07375 (EQH15_07735) | - | 1449737..1450414 (-) | 678 | WP_000221604.1 | DnaD domain-containing protein | - |
| EQH15_RS07380 (EQH15_07740) | metA | 1450423..1451367 (-) | 945 | WP_001122713.1 | homoserine O-succinyltransferase | - |
| EQH15_RS07385 (EQH15_07745) | - | 1451549..1452061 (-) | 513 | WP_001049325.1 | adenine phosphoribosyltransferase | - |
| EQH15_RS07390 (EQH15_07750) | - | 1452149..1452907 (-) | 759 | WP_001287230.1 | class I SAM-dependent methyltransferase | - |
| EQH15_RS07395 | - | 1453115..1453261 (+) | 147 | WP_000403100.1 | hypothetical protein | - |
| EQH15_RS07400 (EQH15_07755) | - | 1453408..1454538 (-) | 1131 | WP_000229959.1 | ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 410 a.a. Molecular weight: 45798.35 Da Isoelectric Point: 4.4550
>NTDB_id=338700 EQH15_RS07345 WP_000106346.1 1444255..1445487(-) (clpX) [Streptococcus pneumoniae strain TVO_1901920]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA
Nucleotide
Download Length: 1233 bp
>NTDB_id=338700 EQH15_RS07345 WP_000106346.1 1444255..1445487(-) (clpX) [Streptococcus pneumoniae strain TVO_1901920]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTGCCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAATAATAAGGCGATTGACGAAAACAGCTCATATATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACTTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATTATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTGCCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAATAATAAGGCGATTGACGAAAACAGCTCATATATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACTTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATTATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpX | Streptococcus mutans UA159 |
86.585 |
100 |
0.866 |
| clpX | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
57.214 |
98.049 |
0.561 |