Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EQH15_RS01940 Genome accession   NZ_CP035265
Coordinates   366272..366961 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901920     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 361272..371961
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH15_RS01915 (EQH15_02000) gpsB 361381..361710 (+) 330 WP_000146522.1 cell division regulator GpsB -
  EQH15_RS01925 (EQH15_02010) - 362196..363353 (+) 1158 WP_000711376.1 class I SAM-dependent RNA methyltransferase -
  EQH15_RS01930 (EQH15_02015) mapZ 363366..364760 (+) 1395 WP_000039299.1 mid-cell-anchored protein MapZ -
  EQH15_RS01935 (EQH15_02020) gndA 364836..366260 (+) 1425 WP_000158786.1 NADP-dependent phosphogluconate dehydrogenase -
  EQH15_RS01940 (EQH15_02025) covR 366272..366961 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  EQH15_RS01945 (EQH15_02030) cbpC 367059..368081 (+) 1023 WP_000771112.1 choline-binding protein CbpC -
  EQH15_RS01950 (EQH15_02035) cbpJ 368100..369098 (+) 999 WP_000771131.1 choline-binding protein CbpJ -
  EQH15_RS01955 (EQH15_02040) - 369216..370448 (-) 1233 WP_000765688.1 MFS transporter -
  EQH15_RS01960 (EQH15_02045) - 370491..371366 (-) 876 WP_010963214.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=338676 EQH15_RS01940 WP_000518018.1 366272..366961(+) (covR) [Streptococcus pneumoniae strain TVO_1901920]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=338676 EQH15_RS01940 WP_000518018.1 366272..366961(+) (covR) [Streptococcus pneumoniae strain TVO_1901920]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment