Detailed information NTG0338646

Bioinformatically predicted

Overview

• Name: comGG/cglG
• Type: Machinery gene
• Locus tag: EQH16_RS09950
• Genome accession: NZ_CP035264
• Coordinates: 1908589..1909002 (-)
• Length: 137 a.a.
• NCBI ID: WP_000265622.1
• Uniprot ID: Q8CY84
• Organism: Streptococcus pneumoniae strain TVO_1901921
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1903589..1914002

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH16_RS09925 (EQH16_10415)	-	1904284..1905108 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
EQH16_RS09930 (EQH16_10420)	rnpA	1905083..1905454 (-)	372	WP_000739246.1	ribonuclease P protein component	-
EQH16_RS11155	-	1905471..1905602 (-)	132	WP_000768904.1	hypothetical protein	-
EQH16_RS09935 (EQH16_10425)	-	1905603..1906793 (-)	1191	WP_000167766.1	acetate kinase	-
EQH16_RS09940 (EQH16_10430)	comYH	1906844..1907797 (-)	954	WP_000345122.1	class I SAM-dependent methyltransferase	Machinery gene
EQH16_RS09945 (EQH16_10435)	-	1907858..1908452 (-)	595	Protein_1962	class I SAM-dependent methyltransferase	-
EQH16_RS09950 (EQH16_10440)	comGG/cglG	1908589..1909002 (-)	414	WP_000265622.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQH16_RS09955 (EQH16_10445)	comGF/cglF	1908980..1909441 (-)	462	WP_000250534.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQH16_RS09960 (EQH16_10450)	comGE/cglE	1909404..1909706 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQH16_RS09965 (EQH16_10455)	comGD/cglD	1909669..1910073 (-)	405	WP_000588026.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQH16_RS09970 (EQH16_10460)	comGC/cglC	1910066..1910392 (-)	327	WP_000738626.1	comG operon protein ComGC	Machinery gene
EQH16_RS09975 (EQH16_10465)	comGB/cglB	1910394..1911410 (-)	1017	WP_074196785.1	competence type IV pilus assembly protein ComGB	Machinery gene
EQH16_RS09980 (EQH16_10470)	comGA/cglA/cilD	1911358..1912299 (-)	942	WP_000249564.1	competence type IV pilus ATPase ComGA	Machinery gene
EQH16_RS09985 (EQH16_10475)	-	1912375..1912740 (-)	366	WP_000286415.1	DUF1033 family protein	-
EQH16_RS09990 (EQH16_10480)	-	1912891..1913949 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 137 a.a.
• Molecular weight: 16003.46 Da
• Isoelectric Point: 10.2472

>NTDB_id=338646 EQH16_RS09950 WP_000265622.1 1908589..1909002(-) (comGG/cglG) [Streptococcus pneumoniae strain TVO_1901921]
MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNKEKLVAFAMAKRTKDKVEQESGEQFFNLGQVSYQNKK
TGLVTRVRTDKSQYEFLFPSVKIKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS

Nucleotide

• Length: 414 bp

>NTDB_id=338646 EQH16_RS09950 WP_000265622.1 1908589..1909002(-) (comGG/cglG) [Streptococcus pneumoniae strain TVO_1901921]
GTGTGGAAAAAGAAAAAAGTTAAGGCAGGTGTTCTCCTCTACGCAGTCACCATAGCAGCCATCTTTAGTCTTTTGTTGCA
ATTTTATTTGAACCGACAAGTCGCCCACTATCAAGACTATGCTTTGAATAAAGAAAAATTGGTTGCTTTTGCTATGGCTA
AACGAACCAAAGATAAGGTTGAGCAAGAAAGTGGGGAACAGTTTTTTAATCTAGGTCAGGTAAGCTATCAAAACAAGAAA
ACTGGCTTAGTGACGAGGGTTCGTACGGATAAGAGCCAATATGAGTTTCTGTTTCCTTCAGTCAAAATCAAAGAAGAGAA
AAGAGATAAAAAGGAAGAGGTAGCGACCGATTCAAGCGAAAAAGTGGAGAAGAAAAAATCAGAAGAGAAGCCTGAAAAGA
AAGAGAATTCATAG

Domains

No domain identified.

3D structure

• AlphaFold DB: Q8CY84

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGG/cglG	Streptococcus pneumoniae Rx1	100	100	1
comGG/cglG	Streptococcus pneumoniae D39	100	100	1
comGG/cglG	Streptococcus pneumoniae R6	100	100	1
comGG/cglG	Streptococcus pneumoniae TIGR4	100	100	1
comGG/cglG	Streptococcus mitis SK321	87.591	100	0.876
comGG/cglG	Streptococcus mitis NCTC 12261	89.256	88.321	0.788
comYG	Streptococcus mutans UA140	38.806	97.81	0.38
comYG	Streptococcus mutans UA159	38.806	97.81	0.38