Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EQH16_RS02210 Genome accession   NZ_CP035264
Coordinates   402370..403059 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901921     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 397370..408059
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH16_RS02185 (EQH16_02265) gpsB 397479..397808 (+) 330 WP_000146522.1 cell division regulator GpsB -
  EQH16_RS02195 (EQH16_02275) - 398294..399451 (+) 1158 WP_000711376.1 class I SAM-dependent RNA methyltransferase -
  EQH16_RS02200 (EQH16_02280) mapZ 399464..400858 (+) 1395 WP_000039299.1 mid-cell-anchored protein MapZ -
  EQH16_RS02205 (EQH16_02285) gndA 400934..402358 (+) 1425 WP_000158786.1 NADP-dependent phosphogluconate dehydrogenase -
  EQH16_RS02210 (EQH16_02290) covR 402370..403059 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  EQH16_RS02215 (EQH16_02295) cbpC 403157..404179 (+) 1023 WP_000771112.1 choline-binding protein CbpC -
  EQH16_RS02220 (EQH16_02300) cbpJ 404198..405196 (+) 999 WP_000771131.1 choline-binding protein CbpJ -
  EQH16_RS02225 (EQH16_02305) - 405314..406546 (-) 1233 WP_000765688.1 MFS transporter -
  EQH16_RS02230 (EQH16_02310) - 406589..407464 (-) 876 WP_010963214.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=338599 EQH16_RS02210 WP_000518018.1 402370..403059(+) (covR) [Streptococcus pneumoniae strain TVO_1901921]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=338599 EQH16_RS02210 WP_000518018.1 402370..403059(+) (covR) [Streptococcus pneumoniae strain TVO_1901921]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment