Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EQH17_RS01735 Genome accession   NZ_CP035263
Coordinates   346803..347492 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901922     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 341803..352492
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH17_RS01710 (EQH17_01835) gpsB 341912..342241 (+) 330 WP_000146522.1 cell division regulator GpsB -
  EQH17_RS01720 (EQH17_01845) - 342727..343884 (+) 1158 WP_000711402.1 class I SAM-dependent RNA methyltransferase -
  EQH17_RS01725 (EQH17_01850) mapZ 343897..345291 (+) 1395 WP_000039289.1 mid-cell-anchored protein MapZ -
  EQH17_RS01730 (EQH17_01855) gndA 345367..346791 (+) 1425 WP_000158786.1 NADP-dependent phosphogluconate dehydrogenase -
  EQH17_RS01735 (EQH17_01860) covR 346803..347492 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  EQH17_RS01740 (EQH17_01865) cbpC 347590..348612 (+) 1023 WP_000771112.1 choline-binding protein CbpC -
  EQH17_RS01745 (EQH17_01870) cbpJ 348631..349629 (+) 999 WP_000771130.1 choline-binding protein CbpJ -
  EQH17_RS01750 (EQH17_01875) - 349747..350979 (-) 1233 WP_000765688.1 MFS transporter -
  EQH17_RS01755 (EQH17_01880) - 351022..351897 (-) 876 WP_014632445.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=338519 EQH17_RS01735 WP_000518018.1 346803..347492(+) (covR) [Streptococcus pneumoniae strain TVO_1901922]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=338519 EQH17_RS01735 WP_000518018.1 346803..347492(+) (covR) [Streptococcus pneumoniae strain TVO_1901922]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment