Detailed information NTG0338442

Bioinformatically predicted

Overview

• Name: covR
• Type: Regulator
• Locus tag: EQH18_RS01775
• Genome accession: NZ_CP035262
• Coordinates: 354564..355253 (+)
• Length: 229 a.a.
• NCBI ID: WP_000518007.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901923
• Function: repress comR expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	355321..356577	354564..355253	flank	68

Gene organization within MGE regions

Location: 354564..356577

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH18_RS01775 (EQH18_01890)	covR	354564..355253 (+)	690	WP_000518007.1	response regulator transcription factor	Regulator
EQH18_RS01780 (EQH18_01895)	-	355321..356577 (-)	1257	WP_238120052.1	ISL3 family transposase	-

Sequence

Protein

• Length: 229 a.a.
• Molecular weight: 26896.17 Da
• Isoelectric Point: 6.9836

>NTDB_id=338442 EQH18_RS01775 WP_000518007.1 354564..355253(+) (covR) [Streptococcus pneumoniae strain TVO_1901923]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTIQE

Nucleotide

• Length: 690 bp

>NTDB_id=338442 EQH18_RS01775 WP_000518007.1 354564..355253(+) (covR) [Streptococcus pneumoniae strain TVO_1901923]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGATTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGTAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATTCAAGAATAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (5-114)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (154-226)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covR	Streptococcus salivarius strain HSISS4	48.696	100	0.489
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.087	100	0.463