Detailed information NTG0338378

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: EQH19_RS04530
• Genome accession: NZ_CP035261
• Coordinates: 900123..902363 (+)
• Length: 746 a.a.
• NCBI ID: WP_000942425.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901924
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 895123..907363

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH19_RS04500 (EQH19_04775)	-	895273..896241 (+)	969	WP_000658183.1	PhoH family protein	-
EQH19_RS04505 (EQH19_04785)	-	896434..896934 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
EQH19_RS04510 (EQH19_04790)	-	896937..897263 (+)	327	Protein_900	TfoX/Sxy family protein	-
EQH19_RS04515	ald	897564..898675 (-)	1112	Protein_901	alanine dehydrogenase	-
EQH19_RS04520 (EQH19_04810)	-	898852..899421 (+)	570	WP_000443775.1	GNAT family N-acetyltransferase	-
EQH19_RS04525 (EQH19_04815)	comEA/celA/cilE	899489..900139 (+)	651	WP_000387332.1	helix-hairpin-helix domain-containing protein	Machinery gene
EQH19_RS04530 (EQH19_04820)	comEC/celB	900123..902363 (+)	2241	WP_000942425.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EQH19_RS10840 (EQH19_04825)	-	902512..902729 (+)	218	Protein_905	hypothetical protein	-
EQH19_RS04535 (EQH19_04830)	-	902762..903349 (+)	588	WP_000939880.1	ATP-binding cassette domain-containing protein	-
EQH19_RS04540 (EQH19_04835)	-	903353..904534 (+)	1182	WP_000655935.1	membrane protein	-
EQH19_RS04545 (EQH19_04840)	infC	904841..905371 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
EQH19_RS04550 (EQH19_04845)	rpmI	905404..905604 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
EQH19_RS04555 (EQH19_04850)	rplT	905656..906015 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
EQH19_RS04560 (EQH19_04855)	-	906073..906453 (+)	381	WP_000157154.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84595.12 Da
• Isoelectric Point: 9.5123

>NTDB_id=338378 EQH19_RS04530 WP_000942425.1 900123..902363(+) (comEC/celB) [Streptococcus pneumoniae strain TVO_1901924]
MLQWIKNIPIPLIYLSFLLLWFYYAIFSASYLALLGFVFLLVCLFFQFPWKSAGKVLVICGVFGFWFLFQNWQQSQASQN
LADSVERVRILPDTVKVNGDSLSFRGKADGRIFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVFLLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLISLPLVYDLRKNIKGLTVLSLLITGLFFLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIKKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
EHVGDLSEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=338378 EQH19_RS04530 WP_000942425.1 900123..902363(+) (comEC/celB) [Streptococcus pneumoniae strain TVO_1901924]
ATGTTACAGTGGATTAAGAACATCCCCATTCCCCTAATTTACCTGAGTTTTTTGTTACTTTGGTTTTATTACGCTATTTT
CTCAGCATCCTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTTTCCAATTTCCATGGAAATCAGCAG
GCAAAGTTTTAGTGATTTGTGGAGTCTTTGGCTTCTGGTTTCTGTTTCAAAATTGGCAACAGAGCCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTCTGCCTGACACTGTTAAGGTCAATGGTGATAGTCTGTCCTTTCGCGGCAA
GGCTGATGGACGCATTTTTCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAACAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACAGTGTTTCTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATC
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTGGAGGGCATTATTCGCTTGGT
CTCACAGGTGGCAAGTAGGCCTCTAGTCTTTGGACAACCCAATGAATGGCTTTTAATCCTATTGTTAATTTCTTTGCCTT
TGGTCTATGATTTGAGGAAAAACATTAAAGGATTAACAGTATTGAGTTTATTGATTACAGGTCTCTTTTTCCTTACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCAAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGGGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGCATGTTGGAGATTTGTCAGAGATGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGATAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (31-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-693)

• Competence protein (Competence) (216-457)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae Rx1	97.453	100	0.975
comEC/celB	Streptococcus pneumoniae D39	97.453	100	0.975
comEC/celB	Streptococcus pneumoniae R6	97.453	100	0.975
comEC/celB	Streptococcus pneumoniae TIGR4	97.319	100	0.973
comEC/celB	Streptococcus mitis SK321	91.689	100	0.917
comEC/celB	Streptococcus mitis NCTC 12261	91.275	99.866	0.912
comEC	Lactococcus lactis subsp. cremoris KW2	43.952	99.732	0.438