Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EQH20_RS01705 Genome accession   NZ_CP035260
Coordinates   342840..343529 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901925     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 337840..348529
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH20_RS01680 (EQH20_01765) gpsB 337949..338278 (+) 330 WP_000146522.1 cell division regulator GpsB -
  EQH20_RS01690 (EQH20_01775) - 338764..339921 (+) 1158 WP_000711385.1 class I SAM-dependent RNA methyltransferase -
  EQH20_RS01695 (EQH20_01780) mapZ 339934..341328 (+) 1395 WP_000039270.1 mid-cell-anchored protein MapZ -
  EQH20_RS01700 (EQH20_01785) gndA 341404..342828 (+) 1425 WP_000158794.1 NADP-dependent phosphogluconate dehydrogenase -
  EQH20_RS01705 (EQH20_01790) covR 342840..343529 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  EQH20_RS01710 (EQH20_01795) - 343627..344529 (+) 903 WP_061636011.1 choline-binding protein CbpC -
  EQH20_RS01715 (EQH20_01800) cbpJ 344548..345546 (+) 999 WP_061636012.1 choline-binding protein CbpJ -
  EQH20_RS01720 (EQH20_01805) - 345582..346838 (-) 1257 WP_238124930.1 ISL3-like element IS1167A family transposase -
  EQH20_RS01725 (EQH20_01810) mvk 347089..347967 (+) 879 WP_061647514.1 mevalonate kinase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=338288 EQH20_RS01705 WP_000518018.1 342840..343529(+) (covR) [Streptococcus pneumoniae strain TVO_1901925]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=338288 EQH20_RS01705 WP_000518018.1 342840..343529(+) (covR) [Streptococcus pneumoniae strain TVO_1901925]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment