Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EQH21_RS01845 Genome accession   NZ_CP035259
Coordinates   356157..356846 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901926     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 351157..361846
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH21_RS01820 (EQH21_01925) gpsB 351266..351595 (+) 330 WP_000146522.1 cell division regulator GpsB -
  EQH21_RS01830 (EQH21_01935) - 352081..353238 (+) 1158 WP_000711391.1 class I SAM-dependent RNA methyltransferase -
  EQH21_RS01835 (EQH21_01940) mapZ 353251..354645 (+) 1395 WP_000039255.1 mid-cell-anchored protein MapZ -
  EQH21_RS01840 (EQH21_01945) gndA 354721..356145 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  EQH21_RS01845 (EQH21_01950) covR 356157..356846 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  EQH21_RS01850 (EQH21_01955) cbpC 356944..357966 (+) 1023 WP_000771113.1 choline-binding protein CbpC -
  EQH21_RS01855 (EQH21_01960) cbpJ 357984..358982 (+) 999 WP_000698048.1 choline-binding protein CbpJ -
  EQH21_RS01860 (EQH21_01965) - 359100..360332 (-) 1233 WP_000765692.1 MFS transporter -
  EQH21_RS01865 (EQH21_01970) - 360375..360962 (-) 588 WP_016397727.1 lanthionine synthetase LanC family protein -
  EQH21_RS01870 (EQH21_01975) - 360862..361251 (-) 390 WP_016397728.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=338212 EQH21_RS01845 WP_000518011.1 356157..356846(+) (covR) [Streptococcus pneumoniae strain TVO_1901926]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=338212 EQH21_RS01845 WP_000518011.1 356157..356846(+) (covR) [Streptococcus pneumoniae strain TVO_1901926]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACACGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGACAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment