Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EQH23_RS01930 Genome accession   NZ_CP035257
Coordinates   374278..374967 (+) Length   229 a.a.
NCBI ID   WP_000518016.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901928     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 369278..379967
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH23_RS01905 (EQH23_02010) gpsB 369387..369716 (+) 330 WP_000146522.1 cell division regulator GpsB -
  EQH23_RS01915 (EQH23_02020) - 370202..371359 (+) 1158 WP_000711391.1 class I SAM-dependent RNA methyltransferase -
  EQH23_RS01920 (EQH23_02025) mapZ 371372..372766 (+) 1395 WP_000039276.1 mid-cell-anchored protein MapZ -
  EQH23_RS01925 (EQH23_02030) gndA 372842..374266 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  EQH23_RS01930 (EQH23_02035) covR 374278..374967 (+) 690 WP_000518016.1 response regulator transcription factor Regulator
  EQH23_RS01935 (EQH23_02040) cbpC 375065..376024 (+) 960 WP_000771106.1 choline-binding protein CbpC -
  EQH23_RS01940 (EQH23_02045) mvk 376146..377024 (+) 879 WP_000163315.1 mevalonate kinase -
  EQH23_RS01945 (EQH23_02050) mvaD 377006..377959 (+) 954 WP_000373458.1 diphosphomevalonate decarboxylase -
  EQH23_RS01950 (EQH23_02055) - 377946..378953 (+) 1008 WP_000562430.1 phosphomevalonate kinase -
  EQH23_RS01955 (EQH23_02060) fni 378937..379947 (+) 1011 WP_000210617.1 type 2 isopentenyl-diphosphate Delta-isomerase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26932.24 Da        Isoelectric Point: 6.9836

>NTDB_id=338055 EQH23_RS01930 WP_000518016.1 374278..374967(+) (covR) [Streptococcus pneumoniae strain TVO_1901928]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=338055 EQH23_RS01930 WP_000518016.1 374278..374967(+) (covR) [Streptococcus pneumoniae strain TVO_1901928]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGTAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment