Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   FTN78_RS04050 Genome accession   NZ_CP043523
Coordinates   736445..737680 (+) Length   411 a.a.
NCBI ID   WP_010905787.1    Uniprot ID   Q9CGE6
Organism   Lactococcus lactis subsp. lactis bv. diacetylactis strain SD96     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 731445..742680
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FTN78_RS04020 (FTN78_chr0778) - 732279..732872 (+) 594 WP_003132093.1 xanthine phosphoribosyltransferase -
  FTN78_RS04025 (FTN78_chr0779) - 732921..734225 (+) 1305 WP_003132095.1 nucleobase:cation symporter-2 family protein -
  FTN78_RS04030 (FTN78_chr0780) - 734254..734667 (-) 414 WP_003132097.1 hypothetical protein -
  FTN78_RS04035 (FTN78_chr0781) - 734787..735296 (-) 510 WP_010905785.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  FTN78_RS04040 (FTN78_chr0782) - 735695..736201 (+) 507 WP_010905786.1 dihydrofolate reductase -
  FTN78_RS04050 (FTN78_chr0784) clpX 736445..737680 (+) 1236 WP_010905787.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  FTN78_RS04055 (FTN78_chr0785) yihA 737677..738264 (+) 588 WP_010905788.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  FTN78_RS04060 (FTN78_chr0786) folB 738318..738668 (+) 351 WP_003132106.1 dihydroneopterin aldolase -
  FTN78_RS04065 (FTN78_chr0787) folE 738748..739797 (+) 1050 WP_010905789.1 GTP cyclohydrolase I FolE -
  FTN78_RS04070 (FTN78_chr0788) folP 739794..740867 (+) 1074 WP_003132109.1 dihydropteroate synthase -
  FTN78_RS04075 (FTN78_chr0789) - 740870..741367 (+) 498 WP_003132112.1 NUDIX domain-containing protein -
  FTN78_RS04080 (FTN78_chr0790) - 741386..742669 (+) 1284 WP_003132113.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 45976.83 Da        Isoelectric Point: 4.6053

>NTDB_id=338014 FTN78_RS04050 WP_010905787.1 736445..737680(+) (clpX) [Lactococcus lactis subsp. lactis bv. diacetylactis strain SD96]
MSNTQNPNIHCSFCGKSQDDVKKLIAGSDVYICNECIELSTRILEEELREEQDSEMLEVKTPKEMFDHLNEYVIGQEKAK
RALAVAVYNHYKRINFAASKIAEDIELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILL
KLLQASDFNIERAERGIIYIDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNI
LFIVGGAFDGIEEIVKQRLGEKIIGFGANNKKLNDDDSYMQEIIAEDIQKFGLIPEFIGRLPIVAALERLTEEDLIQILT
EPKNALIKQYKQLLLFDNVELEFEDEALMAIARKAIERKTGARGLRSIIEEVMMDIMFEVPSHEEITKVIINEAVVDGKA
EPQMIREAKKK

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=338014 FTN78_RS04050 WP_010905787.1 736445..737680(+) (clpX) [Lactococcus lactis subsp. lactis bv. diacetylactis strain SD96]
ATGTCAAATACACAAAATCCAAATATACATTGTTCTTTCTGTGGAAAGAGTCAAGATGATGTAAAAAAATTGATTGCCGG
TTCAGACGTTTATATTTGTAATGAATGTATTGAACTTTCAACTCGAATCTTAGAAGAAGAATTAAGAGAAGAACAAGATT
CAGAAATGCTTGAAGTTAAAACACCTAAAGAAATGTTTGACCATTTAAATGAATATGTGATAGGTCAAGAAAAAGCAAAA
CGTGCACTTGCAGTTGCCGTTTATAATCATTACAAACGAATTAATTTTGCAGCAAGTAAAATTGCTGAAGATATTGAACT
ACAAAAATCAAATATTCTATTAATCGGACCTACCGGTTCTGGTAAGACTTTTCTCGCTCAAACTTTAGCGAAATCACTCA
ACGTTCCATTTGCGATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTTGGAGAAGACGTTGAAAATATTCTCTTA
AAACTTTTACAAGCGAGTGATTTCAATATTGAACGTGCTGAACGTGGAATTATCTATATCGATGAAATTGATAAAATTGC
TAAAAAATCTGAAAATGTATCAATTACTCGTGACGTTTCCGGGGAAGGTGTTCAACAAGCCCTTTTGAAAATTATTGAAG
GAACGGTAGCTAGTGTTCCACCACAAGGTGGACGTAAACATCCTAATCAAGAAATGATTCAAATTGATACCAAAAATATC
TTATTTATTGTTGGTGGAGCTTTTGACGGGATTGAAGAAATTGTCAAACAACGTTTAGGTGAAAAAATTATTGGTTTTGG
TGCCAATAATAAAAAATTAAATGACGATGATTCTTATATGCAAGAAATTATTGCCGAGGACATTCAAAAATTCGGATTAA
TTCCTGAATTTATTGGTCGTCTGCCAATTGTTGCTGCTTTGGAACGTTTGACCGAAGAGGATTTGATTCAAATTTTGACA
GAACCTAAAAATGCTTTGATTAAACAATATAAACAACTCCTTTTATTTGATAATGTTGAACTTGAATTTGAAGATGAAGC
CCTCATGGCAATTGCTAGAAAAGCAATTGAGCGCAAAACAGGAGCGCGTGGACTTCGTTCAATTATTGAAGAAGTAATGA
TGGATATCATGTTTGAAGTTCCAAGTCATGAAGAAATTACAAAAGTTATTATTAATGAAGCAGTTGTTGACGGAAAAGCT
GAGCCACAAATGATTCGAGAGGCCAAGAAAAAATGA

Domains

Predicted by InterProScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(10-46)

AAA domain (Cdc48 subfamily) (AAA_2)

(108-304)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(310-388)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CGE6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

76.559

97.567

0.747
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.883

95.864

0.564