Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EQH24_RS02125 Genome accession   NZ_CP035256
Coordinates   401036..401725 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901930     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 396036..406725
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH24_RS02100 (EQH24_02220) gpsB 396145..396474 (+) 330 WP_000146522.1 cell division regulator GpsB -
  EQH24_RS02110 (EQH24_02230) - 396960..398117 (+) 1158 WP_000711393.1 class I SAM-dependent RNA methyltransferase -
  EQH24_RS02115 (EQH24_02235) mapZ 398130..399524 (+) 1395 WP_023396578.1 mid-cell-anchored protein MapZ -
  EQH24_RS02120 (EQH24_02240) gndA 399600..401024 (+) 1425 WP_023396152.1 NADP-dependent phosphogluconate dehydrogenase -
  EQH24_RS02125 (EQH24_02245) covR 401036..401725 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  EQH24_RS02130 (EQH24_02250) cbpC 401824..402843 (+) 1020 WP_023396153.1 choline-binding protein CbpC -
  EQH24_RS02135 (EQH24_02255) - 402961..404193 (-) 1233 WP_000765673.1 MFS transporter -
  EQH24_RS02140 (EQH24_02260) - 404236..404823 (-) 588 WP_001835194.1 lanthionine synthetase LanC family protein -
  EQH24_RS02145 (EQH24_02265) - 404723..405061 (-) 339 Protein_427 lantibiotic-modifying protein -
  EQH24_RS11820 - 405724..405891 (+) 168 Protein_428 transposase -
  EQH24_RS11825 - 405931..406053 (+) 123 Protein_429 hypothetical protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=337973 EQH24_RS02125 WP_000518011.1 401036..401725(+) (covR) [Streptococcus pneumoniae strain TVO_1901930]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=337973 EQH24_RS02125 WP_000518011.1 401036..401725(+) (covR) [Streptococcus pneumoniae strain TVO_1901930]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment