Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EQH26_RS02065 Genome accession   NZ_CP035254
Coordinates   390890..391579 (+) Length   229 a.a.
NCBI ID   WP_000518016.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901932     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 385890..396579
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH26_RS02040 (EQH26_02170) gpsB 386000..386329 (+) 330 WP_000146522.1 cell division regulator GpsB -
  EQH26_RS02050 (EQH26_02180) - 386815..387972 (+) 1158 WP_000711375.1 class I SAM-dependent RNA methyltransferase -
  EQH26_RS02055 (EQH26_02185) mapZ 387984..389378 (+) 1395 WP_000039304.1 mid-cell-anchored protein MapZ -
  EQH26_RS02060 (EQH26_02190) gndA 389454..390878 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  EQH26_RS02065 (EQH26_02195) covR 390890..391579 (+) 690 WP_000518016.1 response regulator transcription factor Regulator
  EQH26_RS02070 (EQH26_02200) cbpC 391677..392642 (+) 966 WP_054369578.1 choline-binding protein CbpC -
  EQH26_RS02075 (EQH26_02205) cbpJ 392661..393659 (+) 999 WP_000771132.1 choline-binding protein CbpJ -
  EQH26_RS02080 (EQH26_02210) - 393777..395009 (-) 1233 WP_000765681.1 MFS transporter -
  EQH26_RS02085 (EQH26_02215) - 395168..395638 (-) 471 WP_001809487.1 lanthionine synthetase LanC family protein -
  EQH26_RS02090 (EQH26_02220) - 395538..395927 (-) 390 WP_255313994.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26932.24 Da        Isoelectric Point: 6.9836

>NTDB_id=337894 EQH26_RS02065 WP_000518016.1 390890..391579(+) (covR) [Streptococcus pneumoniae strain TVO_1901932]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=337894 EQH26_RS02065 WP_000518016.1 390890..391579(+) (covR) [Streptococcus pneumoniae strain TVO_1901932]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGTAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment