Detailed information NTG0337858

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EQH28_RS09645
• Genome accession: NZ_CP035252
• Coordinates: 1881522..1882559 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727276.1
• Uniprot ID: A0AAQ2ZXI6
• Organism: Streptococcus pneumoniae strain TVO_1901934
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1876522..1887559

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH28_RS09620 (EQH28_10165)	-	1877261..1878592 (-)	1332	WP_000390039.1	hemolysin family protein	-
EQH28_RS09625 (EQH28_10170)	endA	1878883..1879707 (-)	825	WP_047474853.1	DNA-entry nuclease EndA	Machinery gene
EQH28_RS09630 (EQH28_10175)	-	1879746..1879934 (-)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
EQH28_RS09635 (EQH28_10180)	murA	1879927..1881210 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
EQH28_RS09640 (EQH28_10185)	-	1881234..1881464 (-)	231	WP_000250392.1	DUF1146 family protein	-
EQH28_RS09645 (EQH28_10190)	sepM	1881522..1882559 (-)	1038	WP_000727276.1	SepM family pheromone-processing serine protease	Regulator
EQH28_RS09650 (EQH28_10195)	coaD	1882543..1883031 (-)	489	WP_001280742.1	pantetheine-phosphate adenylyltransferase	-
EQH28_RS09655 (EQH28_10200)	rsmD	1883021..1883560 (-)	540	WP_000706962.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EQH28_RS09660 (EQH28_10205)	asnA	1883625..1884617 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
EQH28_RS09665 (EQH28_10215)	-	1884729..1885412 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
EQH28_RS09670 (EQH28_10220)	-	1885468..1886208 (-)	741	WP_000152701.1	RNA methyltransferase	-
EQH28_RS09675 (EQH28_10225)	-	1886242..1886520 (+)	279	WP_001174613.1	acylphosphatase	-
EQH28_RS09680 (EQH28_10230)	yidC	1886598..1887524 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37553.61 Da
• Isoelectric Point: 5.0724

>NTDB_id=337858 EQH28_RS09645 WP_000727276.1 1881522..1882559(-) (sepM) [Streptococcus pneumoniae strain TVO_1901934]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=337858 EQH28_RS09645 WP_000727276.1 1881522..1882559(-) (sepM) [Streptococcus pneumoniae strain TVO_1901934]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCTGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588