Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   EQH28_RS09625 Genome accession   NZ_CP035252
Coordinates   1878883..1879707 (-) Length   274 a.a.
NCBI ID   WP_047474853.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901934     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1873883..1884707
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH28_RS09620 (EQH28_10165) - 1877261..1878592 (-) 1332 WP_000390039.1 hemolysin family protein -
  EQH28_RS09625 (EQH28_10170) endA 1878883..1879707 (-) 825 WP_047474853.1 DNA-entry nuclease EndA Machinery gene
  EQH28_RS09630 (EQH28_10175) - 1879746..1879934 (-) 189 WP_001813390.1 DNA-directed RNA polymerase subunit beta -
  EQH28_RS09635 (EQH28_10180) murA 1879927..1881210 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  EQH28_RS09640 (EQH28_10185) - 1881234..1881464 (-) 231 WP_000250392.1 DUF1146 family protein -
  EQH28_RS09645 (EQH28_10190) sepM 1881522..1882559 (-) 1038 WP_000727276.1 SepM family pheromone-processing serine protease Regulator
  EQH28_RS09650 (EQH28_10195) coaD 1882543..1883031 (-) 489 WP_001280742.1 pantetheine-phosphate adenylyltransferase -
  EQH28_RS09655 (EQH28_10200) rsmD 1883021..1883560 (-) 540 WP_000706962.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  EQH28_RS09660 (EQH28_10205) asnA 1883625..1884617 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29955.61 Da        Isoelectric Point: 10.1197

>NTDB_id=337857 EQH28_RS09625 WP_047474853.1 1878883..1879707(-) (endA) [Streptococcus pneumoniae strain TVO_1901934]
MNKKTRQTLIGLLVLLFLSTGSYYIKQMQSAPNSPKTNLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=337857 EQH28_RS09625 WP_047474853.1 1878883..1879707(-) (endA) [Streptococcus pneumoniae strain TVO_1901934]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGTTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGGCACCTAATAGTCCCAAAACCAATCTTAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

99.27

100

0.993
  endA Streptococcus pneumoniae D39

99.27

100

0.993
  endA Streptococcus pneumoniae R6

99.27

100

0.993
  endA Streptococcus pneumoniae TIGR4

99.27

100

0.993

Multiple sequence alignment