Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EQH28_RS01780 Genome accession   NZ_CP035252
Coordinates   342336..343025 (+) Length   229 a.a.
NCBI ID   WP_047474084.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901934     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 337336..348025
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH28_RS01755 (EQH28_01855) gpsB 337469..337798 (+) 330 WP_000146522.1 cell division regulator GpsB -
  EQH28_RS01765 (EQH28_01865) - 338284..339441 (+) 1158 WP_050230812.1 class I SAM-dependent RNA methyltransferase -
  EQH28_RS01770 (EQH28_01870) mapZ 339454..340824 (+) 1371 WP_000039301.1 mid-cell-anchored protein MapZ -
  EQH28_RS01775 (EQH28_01875) gndA 340900..342324 (+) 1425 WP_000158799.1 NADP-dependent phosphogluconate dehydrogenase -
  EQH28_RS01780 (EQH28_01880) covR 342336..343025 (+) 690 WP_047474084.1 response regulator transcription factor Regulator
  EQH28_RS01785 (EQH28_01885) - 343123..344019 (+) 897 WP_000771107.1 choline-binding protein CbpC -
  EQH28_RS01790 (EQH28_01890) - 344137..345369 (-) 1233 WP_000765684.1 MFS transporter -
  EQH28_RS01795 (EQH28_01895) - 345528..345998 (-) 471 WP_001809487.1 lanthionine synthetase LanC family protein -
  EQH28_RS01800 (EQH28_01900) - 345898..346236 (-) 339 WP_001820155.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26917.27 Da        Isoelectric Point: 7.3523

>NTDB_id=337810 EQH28_RS01780 WP_047474084.1 342336..343025(+) (covR) [Streptococcus pneumoniae strain TVO_1901934]
MGKRILLLEKERNLARFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=337810 EQH28_RS01780 WP_047474084.1 342336..343025(+) (covR) [Streptococcus pneumoniae strain TVO_1901934]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCGTTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment