Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   EQH31_RS09965 Genome accession   NZ_CP035249
Coordinates   1933694..1933996 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901938     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1928694..1938996
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH31_RS09940 (EQH31_10550) comYH 1929499..1930452 (-) 954 WP_000345118.1 class I SAM-dependent methyltransferase Machinery gene
  EQH31_RS09945 (EQH31_10555) - 1930798..1931599 (+) 802 WP_128887635.1 IS5 family transposase -
  EQH31_RS09950 (EQH31_10560) - 1931750..1932226 (+) 477 WP_000777686.1 GNAT family N-acetyltransferase -
  EQH31_RS09955 (EQH31_10565) comGG/cglG 1932900..1933292 (-) 393 WP_001818966.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH31_RS09960 (EQH31_10570) comGF/cglF 1933270..1933731 (-) 462 WP_000250537.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH31_RS09965 (EQH31_10575) comGE/cglE 1933694..1933996 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH31_RS09970 (EQH31_10580) comGD/cglD 1933959..1934363 (-) 405 WP_000588017.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH31_RS09975 (EQH31_10585) comGC/cglC 1934356..1934682 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  EQH31_RS09980 (EQH31_10590) comGB/cglB 1934684..1935700 (-) 1017 WP_001844019.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQH31_RS09985 (EQH31_10595) comGA/cglA/cilD 1935648..1936589 (-) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  EQH31_RS09990 (EQH31_10600) - 1936665..1937030 (-) 366 WP_000286415.1 DUF1033 family protein -
  EQH31_RS09995 (EQH31_10605) - 1937181..1938239 (-) 1059 WP_000649471.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=337704 EQH31_RS09965 WP_000413382.1 1933694..1933996(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901938]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=337704 EQH31_RS09965 WP_000413382.1 1933694..1933996(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901938]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment