Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EQH34_RS01810 Genome accession   NZ_CP035246
Coordinates   364877..365566 (+) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae strain TVO_1901941     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 359877..370566
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH34_RS01785 (EQH34_01920) gpsB 359986..360315 (+) 330 WP_000146522.1 cell division regulator GpsB -
  EQH34_RS01795 (EQH34_01930) - 360801..361958 (+) 1158 WP_000711385.1 class I SAM-dependent RNA methyltransferase -
  EQH34_RS01800 (EQH34_01935) mapZ 361971..363365 (+) 1395 WP_000039310.1 mid-cell-anchored protein MapZ -
  EQH34_RS01805 (EQH34_01940) gndA 363441..364865 (+) 1425 WP_000158798.1 NADP-dependent phosphogluconate dehydrogenase -
  EQH34_RS01810 (EQH34_01945) covR 364877..365566 (+) 690 WP_000518008.1 response regulator transcription factor Regulator
  EQH34_RS01815 (EQH34_01950) - 365665..366567 (+) 903 WP_000771052.1 choline-binding protein CbpC -
  EQH34_RS01820 (EQH34_01955) - 366585..367460 (+) 876 WP_000698049.1 choline-binding protein CbpJ -
  EQH34_RS01825 (EQH34_01960) - 367578..368810 (-) 1233 WP_000765683.1 MFS transporter -
  EQH34_RS01830 (EQH34_01965) - 368969..369727 (-) 759 WP_229294017.1 lanthionine synthetase LanC family protein -
  EQH34_RS10610 - 370342..370509 (+) 168 Protein_361 transposase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=337421 EQH34_RS01810 WP_000518008.1 364877..365566(+) (covR) [Streptococcus pneumoniae strain TVO_1901941]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=337421 EQH34_RS01810 WP_000518008.1 364877..365566(+) (covR) [Streptococcus pneumoniae strain TVO_1901941]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCACGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGTAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment