Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   EQH36_RS10595 Genome accession   NZ_CP035244
Coordinates   2066012..2067310 (-) Length   432 a.a.
NCBI ID   WP_061758440.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901945     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2061012..2072310
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH36_RS10575 (EQH36_11095) rplI 2062167..2062619 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  EQH36_RS10580 (EQH36_11100) - 2062616..2064589 (-) 1974 WP_000715108.1 DHH family phosphoesterase -
  EQH36_RS10585 (EQH36_11105) hpf 2064725..2065273 (-) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  EQH36_RS10590 (EQH36_11110) comFC/cflB 2065353..2066015 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  EQH36_RS10595 (EQH36_11115) comFA/cflA 2066012..2067310 (-) 1299 WP_061758440.1 DEAD/DEAH box helicase Machinery gene
  EQH36_RS10600 (EQH36_11120) - 2067366..2068001 (+) 636 WP_000395739.1 YigZ family protein -
  EQH36_RS10605 (EQH36_11125) cysK 2068286..2069206 (+) 921 WP_000029867.1 cysteine synthase A -
  EQH36_RS10610 (EQH36_11135) - 2069445..2069819 (-) 375 Protein_2082 IS66 family transposase -
  EQH36_RS10615 (EQH36_11140) - 2069792..2070079 (+) 288 Protein_2083 transposase -
  EQH36_RS10620 (EQH36_11145) tnpB 2070220..2070435 (-) 216 WP_000376912.1 IS66 family insertion sequence element accessory protein TnpB -
  EQH36_RS10625 (EQH36_11150) tsf 2070789..2071829 (-) 1041 WP_000808062.1 translation elongation factor Ts -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49591.53 Da        Isoelectric Point: 8.4382

>NTDB_id=337327 EQH36_RS10595 WP_061758440.1 2066012..2067310(-) (comFA/cflA) [Streptococcus pneumoniae strain TVO_1901945]
MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCNSTILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQ
EDFPKQDVLKWRGQLTPFQEKVSEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTLYHAVKNSVKENGLRIFLTATST
NELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSDFNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEI
LQEQFPNEKIGFVSSVTEDRLEQVQVFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=337327 EQH36_RS10595 WP_061758440.1 2066012..2067310(-) (comFA/cflA) [Streptococcus pneumoniae strain TVO_1901945]
ATGAAAGTAAATTTAGATTATCTCGGTCGTTTATTTACTGAGAATGAATTAACAGAAGAAGAACGTCAGTTGGCGGAGAA
ACTTCCAGCAATGAGAAAGGAGAAGGGGAAACTTTTCTGTCAACGTTGTAATAGTACTATTCTAGAAGAATGGTATTTGC
CCATCGGTGCTTACTATTGTCGAGAGTGCTTGCTGATGAAGCGAGTCAGAAGTGATCAAACTTTATACTATTTTCCGCAG
GAGGATTTTCCGAAGCAAGATGTTCTCAAATGGCGCGGCCAATTAACTCCTTTTCAAGAGAAGGTGTCAGAGGGACTGCT
TCAAGCAGTAGACAAGCAAAAGCCAACCTTAGTTCATGCGGTAACAGGAGCTGGAAAGACAGAAATGATTTATCAAGTAG
TGGCTAAAGTGATCAATGCGGGTGGTGCAGTGTGTTTGGCTAGTCCTCGCATAGATGTTTGTTTGGAGCTGTACAAGCGC
CTGCAACAGGATTTTTCTTGCGGGATAGCTTTGCTACATGGAGAATCGGAACCTTATTTTCGAACACCACTAGTTGTTGC
AACAACCCATCAGTTATTGAAGTTTTATCAAGCTTTTGATTTGCTGATAGTGGATGAAGTAGATGCTTTTCCTTATGTTG
ATAATCCCACGCTTTACCACGCTGTCAAGAATAGTGTAAAGGAGAATGGATTGAGAATCTTTTTAACAGCGACTTCGACC
AATGAGTTAGATAAAAAGGTCCGTTTAGGAGAACTAAAAAGACTGAGTTTACCGAGACGGTTTCATGGAAATCCGTTGAT
TATTCCAAAACCAATTTGGTTATCGGATTTTAATCGCTACTTAGACAAGAATCGTTTGTCACCAAAGTTAAAGTCCTATA
TTGAGAAGCAGAGAAAGACAGCTTATCCGTTACTCATTTTTGCTTCAGAAATTAAGAAAGGGGAGCAGTTAGAAGAAATC
TTACAGGAGCAATTTCCAAATGAGAAAATTGGCTTTGTATCTTCTGTAACAGAGGATCGATTAGAGCAAGTACAAGTTTT
TCGAGATGGAGAACTGACAATACTTATCAGTACGACAATCTTGGAGCGTGGAGTTACCTTCCCTTGTGTGGATGTTTTCG
TAGTAGAGGCCAATCATCGTTTGTTTACCAAGTCTAGTTTGATTCAGATTGGTGGACGAGTTGGACGAAGCATGGATAGA
CCGACAGGAGATTTGCTTTTCTTCCATGATGGGTTAAATGCTTCAATCAAGAAGGCGATTAAGGAAATTCAGATGATGAA
TAAGGAGGCTGGTCTATGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-238)

Helicase conserved C-terminal domain (Helicase_C)

(293-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

99.074

100

0.991
  comFA/cflA Streptococcus pneumoniae D39

99.074

100

0.991
  comFA/cflA Streptococcus pneumoniae R6

99.074

100

0.991
  comFA/cflA Streptococcus pneumoniae TIGR4

98.843

100

0.988
  comFA/cflA Streptococcus mitis NCTC 12261

93.287

100

0.933
  comFA/cflA Streptococcus mitis SK321

92.13

100

0.921
  comFA Lactococcus lactis subsp. cremoris KW2

51.716

94.444

0.488
  comFA Latilactobacillus sakei subsp. sakei 23K

38.515

99.769

0.384

Multiple sequence alignment