Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EQH38_RS09820 Genome accession   NZ_CP035242
Coordinates   1926141..1926830 (-) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae strain TVO_1901947     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1921141..1931830
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH38_RS09800 (EQH38_10360) - 1922098..1923105 (-) 1008 WP_000562411.1 phosphomevalonate kinase -
  EQH38_RS09805 (EQH38_10365) mvaD 1923092..1924045 (-) 954 WP_000373458.1 diphosphomevalonate decarboxylase -
  EQH38_RS09810 (EQH38_10370) mvk 1924027..1924905 (-) 879 WP_000163322.1 mevalonate kinase -
  EQH38_RS09815 (EQH38_10375) cbpC 1925027..1926043 (-) 1017 WP_000771103.1 choline-binding protein CbpC -
  EQH38_RS09820 (EQH38_10380) covR 1926141..1926830 (-) 690 WP_000518008.1 response regulator transcription factor Regulator
  EQH38_RS09825 (EQH38_10385) gndA 1926842..1928266 (-) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  EQH38_RS09830 (EQH38_10390) mapZ 1928342..1929736 (-) 1395 WP_054366278.1 mid-cell-anchored protein MapZ -
  EQH38_RS09835 (EQH38_10395) - 1929749..1930906 (-) 1158 WP_050123267.1 class I SAM-dependent RNA methyltransferase -
  EQH38_RS09845 (EQH38_10405) gpsB 1931392..1931721 (-) 330 WP_000146522.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=337163 EQH38_RS09820 WP_000518008.1 1926141..1926830(-) (covR) [Streptococcus pneumoniae strain TVO_1901947]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=337163 EQH38_RS09820 WP_000518008.1 1926141..1926830(-) (covR) [Streptococcus pneumoniae strain TVO_1901947]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment