Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   EQH38_RS02695 Genome accession   NZ_CP035242
Coordinates   489984..490604 (+) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain TVO_1901947     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 484984..495604
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH38_RS02680 (EQH38_02810) - 485743..486375 (-) 633 WP_000571415.1 ABC transporter ATP-binding protein -
  EQH38_RS02685 (EQH38_02815) - 486377..488392 (-) 2016 WP_000732377.1 DUF1430 domain-containing protein -
  EQH38_RS02690 (EQH38_02820) - 488738..489601 (+) 864 WP_001844931.1 helix-turn-helix domain-containing protein -
  EQH38_RS02695 (EQH38_02830) comM 489984..490604 (+) 621 WP_000839908.1 hypothetical protein Regulator
  EQH38_RS02700 (EQH38_02835) tsaE 490691..491134 (+) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  EQH38_RS02705 (EQH38_02840) - 491124..491642 (+) 519 WP_000455536.1 GNAT family N-acetyltransferase -
  EQH38_RS02710 (EQH38_02845) brpA 491650..492666 (+) 1017 WP_001844932.1 biofilm formation/cell division transcriptional regulator BrpA -
  EQH38_RS02715 (EQH38_02850) cinA 492751..494007 (+) 1257 WP_000642709.1 competence/damage-inducible protein A Machinery gene
  EQH38_RS02720 (EQH38_02855) recA 494062..495228 (+) 1167 WP_001085463.1 recombinase RecA Machinery gene

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=337122 EQH38_RS02695 WP_000839908.1 489984..490604(+) (comM) [Streptococcus pneumoniae strain TVO_1901947]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=337122 EQH38_RS02695 WP_000839908.1 489984..490604(+) (comM) [Streptococcus pneumoniae strain TVO_1901947]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCTTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment