Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EQH39_RS01670 Genome accession   NZ_CP035241
Coordinates   335864..336553 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901948     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 330864..341553
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH39_RS01645 (EQH39_01735) gpsB 330974..331303 (+) 330 WP_000146522.1 cell division regulator GpsB -
  EQH39_RS01655 (EQH39_01745) - 331789..332946 (+) 1158 WP_000711388.1 class I SAM-dependent RNA methyltransferase -
  EQH39_RS01660 (EQH39_01750) mapZ 332958..334352 (+) 1395 WP_000039304.1 mid-cell-anchored protein MapZ -
  EQH39_RS01665 (EQH39_01755) gndA 334428..335852 (+) 1425 WP_000158788.1 NADP-dependent phosphogluconate dehydrogenase -
  EQH39_RS01670 (EQH39_01760) covR 335864..336553 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  EQH39_RS01675 (EQH39_01765) cbpC 336651..337667 (+) 1017 WP_000771103.1 choline-binding protein CbpC -
  EQH39_RS01680 (EQH39_01770) mvk 337789..338667 (+) 879 WP_000163315.1 mevalonate kinase -
  EQH39_RS01685 (EQH39_01775) mvaD 338649..339602 (+) 954 WP_000373457.1 diphosphomevalonate decarboxylase -
  EQH39_RS01690 (EQH39_01780) - 339589..340596 (+) 1008 WP_000562428.1 phosphomevalonate kinase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=337033 EQH39_RS01670 WP_000518018.1 335864..336553(+) (covR) [Streptococcus pneumoniae strain TVO_1901948]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=337033 EQH39_RS01670 WP_000518018.1 335864..336553(+) (covR) [Streptococcus pneumoniae strain TVO_1901948]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment