Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FZN32_RS01325 Genome accession   NZ_CP043406
Coordinates   267403..268059 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain NMBU-W13E19     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 262403..273059
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FZN32_RS01295 (FZN32_01380) dcyD 263282..264268 (+) 987 WP_001128228.1 D-cysteine desulfhydrase -
  FZN32_RS01300 (FZN32_01385) tcyL 264283..264951 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  FZN32_RS01305 (FZN32_01390) tcyN 264948..265700 (+) 753 WP_001272982.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FZN32_RS01310 (FZN32_01395) sdiA 265930..266652 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  FZN32_RS01315 (FZN32_01400) yecF 266720..266944 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  FZN32_RS01320 (FZN32_01405) yecU 266931..267107 (-) 177 WP_000590347.1 protein YecU -
  FZN32_RS01325 (FZN32_01410) letA 267403..268059 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FZN32_RS01330 (FZN32_01415) uvrC 268056..269888 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  FZN32_RS01335 (FZN32_01420) pgsA 269945..270493 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FZN32_RS01355 (FZN32_01440) yecA 271143..271808 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=336903 FZN32_RS01325 WP_000611328.1 267403..268059(+) (letA) [Escherichia coli strain NMBU-W13E19]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=336903 FZN32_RS01325 WP_000611328.1 267403..268059(+) (letA) [Escherichia coli strain NMBU-W13E19]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTAGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482