Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   FY406_RS05675 Genome accession   NZ_CP043405
Coordinates   1145332..1145973 (+) Length   213 a.a.
NCBI ID   WP_003086444.1    Uniprot ID   A0ABP2R1I3
Organism   Streptococcus ratti strain ATCC 31377     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1140332..1150973
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FY406_RS05655 (FY406_05655) - 1140908..1141651 (+) 744 WP_003086437.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  FY406_RS05660 (FY406_05660) pknB 1141648..1143510 (+) 1863 WP_150881013.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  FY406_RS05665 (FY406_05665) liaF 1143643..1144338 (+) 696 WP_003086440.1 cell wall-active antibiotics response protein LiaF -
  FY406_RS05670 (FY406_05670) - 1144335..1145339 (+) 1005 WP_003086442.1 sensor histidine kinase -
  FY406_RS05675 (FY406_05675) vraR 1145332..1145973 (+) 642 WP_003086444.1 response regulator transcription factor Regulator
  FY406_RS05680 (FY406_05680) - 1146017..1147429 (+) 1413 WP_003086446.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  FY406_RS05685 (FY406_05685) - 1147416..1147793 (+) 378 WP_003086447.1 S1 RNA-binding domain-containing protein -
  FY406_RS05690 (FY406_05690) cysK 1147983..1148909 (-) 927 WP_003086449.1 cysteine synthase A -
  FY406_RS05695 (FY406_05695) - 1149004..1149633 (-) 630 WP_003086451.1 YigZ family protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23766.35 Da        Isoelectric Point: 4.6531

>NTDB_id=336861 FY406_RS05675 WP_003086444.1 1145332..1145973(+) (vraR) [Streptococcus ratti strain ATCC 31377]
MSKIKVILVDDHEMVRLGLKSFLDLQADVEVVGEAGNGRQGIELALQLKPDVVVMDLVMPEMDGVEATLELLKEWKDAKI
LVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIKKVAKGDLAIETEVDKKIKAHHDNPDLHEDLTARERDILELLA
KGYDNQTIADELFISLKTVKTHVSNILSKLQVDDRTQAVVYAFQHHLVPQDDD

Nucleotide


Download         Length: 642 bp        

>NTDB_id=336861 FY406_RS05675 WP_003086444.1 1145332..1145973(+) (vraR) [Streptococcus ratti strain ATCC 31377]
ATGAGTAAAATAAAGGTTATCCTGGTTGATGACCATGAGATGGTAAGACTGGGTCTGAAGAGTTTTCTTGATTTGCAGGC
AGATGTTGAGGTTGTCGGAGAAGCTGGCAATGGCCGTCAAGGGATTGAGCTGGCCTTACAATTGAAGCCTGATGTTGTTG
TGATGGATCTTGTCATGCCTGAGATGGATGGGGTTGAGGCGACGCTTGAGCTTTTGAAGGAATGGAAAGACGCTAAAATT
TTAGTGCTGACCAGCTATCTTGATAATGAAAAGATTTATCCTGTTATCGAGGCAGGAGCCAAGGGTTATATGCTGAAAAC
ATCCAGCGCTGCAGAAATTTTAAATGCCATCAAAAAAGTTGCCAAAGGTGATTTGGCGATTGAAACGGAAGTTGATAAGA
AAATCAAAGCCCATCATGATAATCCTGATTTGCATGAGGATTTGACCGCTCGGGAGAGAGATATTTTGGAGCTGCTCGCT
AAAGGTTATGACAATCAAACAATAGCTGATGAACTTTTTATCTCTTTAAAAACGGTAAAAACTCATGTGTCCAATATTCT
ATCGAAACTACAGGTGGATGATCGGACACAGGCAGTAGTCTATGCTTTTCAGCATCATTTGGTACCGCAGGATGACGATT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.942

96.714

0.502
  degU Bacillus subtilis subsp. subtilis str. 168

36.726

100

0.39

Multiple sequence alignment