Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   EQH45_RS09350 Genome accession   NZ_CP035235
Coordinates   1830955..1831575 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain TVO_1902276     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1825955..1836575
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH45_RS09325 (EQH45_09825) recA 1826332..1827498 (-) 1167 WP_001085462.1 recombinase RecA Machinery gene
  EQH45_RS09330 (EQH45_09830) cinA 1827553..1828809 (-) 1257 WP_000642709.1 competence/damage-inducible protein A Machinery gene
  EQH45_RS09335 (EQH45_09835) brpA 1828894..1829910 (-) 1017 WP_000239278.1 biofilm formation/cell division transcriptional regulator BrpA -
  EQH45_RS09340 (EQH45_09840) - 1829918..1830436 (-) 519 WP_000455535.1 GNAT family N-acetyltransferase -
  EQH45_RS09345 (EQH45_09845) tsaE 1830426..1830869 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  EQH45_RS09350 (EQH45_09850) comM 1830955..1831575 (-) 621 WP_000839908.1 hypothetical protein Regulator
  EQH45_RS09355 (EQH45_09860) - 1831958..1832821 (-) 864 WP_001093618.1 helix-turn-helix domain-containing protein -
  EQH45_RS11105 (EQH45_09865) - 1833013..1833183 (+) 171 WP_001227862.1 PhrA family quorum-sensing system peptide -
  EQH45_RS09360 (EQH45_09870) pneA1 1833286..1833510 (+) 225 WP_000181086.1 two-peptide bacteriocin subunit PneA1 -
  EQH45_RS09365 (EQH45_09875) pneA2 1833517..1833705 (+) 189 WP_000786759.1 two-peptide bacteriocin subunit PneA2 -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=336690 EQH45_RS09350 WP_000839908.1 1830955..1831575(-) (comM) [Streptococcus pneumoniae strain TVO_1902276]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=336690 EQH45_RS09350 WP_000839908.1 1830955..1831575(-) (comM) [Streptococcus pneumoniae strain TVO_1902276]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment