Detailed information NTG0336571

Bioinformatically predicted

Overview

• Name: amiA3
• Type: Regulator
• Locus tag: EQH46_RS01755
• Genome accession: NZ_CP035234
• Coordinates: 344182..346164 (+)
• Length: 660 a.a.
• NCBI ID: WP_000842784.1
• Uniprot ID: A0A6I3TKG5
• Organism: Streptococcus pneumoniae strain TVO_1902277
• Function: binding to XIP (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	340959..343872	344182..346164	flank	310

Gene organization within MGE regions

Location: 340959..346164

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH46_RS01745 (EQH46_01860)	-	340959..342215 (-)	1257	WP_000436461.1	ISL3-like element IS1167A family transposase	-
EQH46_RS01750 (EQH46_01865)	-	342526..343872 (-)	1347	WP_001808790.1	IS1380-like element ISSpn5 family transposase	-
EQH46_RS01755 (EQH46_01870)	amiA3	344182..346164 (+)	1983	WP_000842784.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 660 a.a.
• Molecular weight: 73124.73 Da
• Isoelectric Point: 4.7570

>NTDB_id=336571 EQH46_RS01755 WP_000842784.1 344182..346164(+) (amiA3) [Streptococcus pneumoniae strain TVO_1902277]
MKSSRLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDPDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPS
MAEDWSVSKDGLTYTYTIRKDAKWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGPYLLKSIVTKSSVEFAKNPNYWD
KDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARLYPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSK
TSEEQKTSTKKALLNKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVTYGDEWKDV
NLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQRVQSMKQSLEATLGADNVVIDIQQLQKDEV
NNITYFAENAAGEDWDLSDNVGWGPDFADPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETT
DVAKRYDKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQDKAVTVDEYQKAQEKW
MKEKEESNKKAQEDLAKHVK

Nucleotide

• Length: 1983 bp

>NTDB_id=336571 EQH46_RS01755 WP_000842784.1 344182..346164(+) (amiA3) [Streptococcus pneumoniae strain TVO_1902277]
ATGAAAAGTTCAAGACTATTTGCCCTTGCGGGCGTGACATTATTGGCGGCGACTACTTTAGCTGCATGCTCTGGATCAGG
TTCAAGCACTAAAGGTGAGAAGACATTCTCATACATTTATGAGACAGACCCTGATAACCTCAACTATTTGACAACTGCTA
AGGCTGCGACAGCAAATATTACCAGTAACGTGGTTGATGGTTTGCTAGAAAATGATCGCTACGGGAACTTTGTGCCGTCT
ATGGCTGAGGATTGGTCTGTATCCAAGGATGGATTGACTTACACTTATACTATCCGTAAGGATGCAAAATGGTATACTTC
TGAAGGTGAAGAATACGCGGCAGTCAAAGCTCAAGACTTTGTAACAGGACTAAAATATGCTGCTGATAAAAAATCAGATG
CTCTTTACCTTGTTCAAGAATCAATCAAAGGGTTGGATGCCTATGTAAAAGGGGAAATCAAAGATTTCTCACAAGTAGGA
ATTAAGGCTCTGGATGAACAGACAGTTCAGTACACTTTGAACAAACCAGAAAGCTTCTGGAATTCTAAGACAACCATGGG
TGTGCTTGCGCCAGTTAATGAAGAGTTTTTGAATTCAAAAGGGGATGATTTTGCCAAAGCTACGGATCCAAGTAGTCTCT
TGTATAACGGTCCTTATTTGTTGAAATCCATTGTGACCAAATCTTCTGTTGAATTTGCGAAAAATCCGAACTACTGGGAT
AAGGACAATGTGCATATTGACAAAGTTAAATTGTCATTCTGGGATGGTCAAGATACCAGCAAACCTGCAGAAAACTTTAA
AGATGGTAGCCTTACAGCAGCTCGTCTCTATCCAACAAGTGCAAGTTTCGCAGAGCTTGAGAAGAGTATGAAGGACAATA
TTGTCTATACTCAACAAGACTCTATTACGTATCTAGTTGGTACAAATATTGACCGTCAGTCCTATAAATATACATCTAAG
ACCAGTGAAGAACAAAAAACATCTACGAAAAAGGCTCTCTTAAACAAGGATTTCCGTCAGGCTATTGCATTTGGATTTGA
CCGTACAGCCTATGCCTCTCAGTTGAATGGACAAACTGGAGCAAGCAAAATCTTACGTAATATCTTTGTTCCACCAACAT
TTGTTCAAGCAGATGGTAAAAACTTTGGCGATATGGTCAAAGAGAAATTGGTCACTTATGGGGATGAATGGAAGGATGTT
AATCTTGCAGATTCTCAGGATGGTCTTTACAATCCAGAAAAAGCCAAGGCTGAATTTGCTAAAGCTAAATCAGCTTTACA
AGCAGAAGGTGTGACTTTCCCAATTCATTTGGATATGCCAGTTGACCAGACAGCAACTACAAAAGTTCAGCGCGTCCAAT
CTATGAAACAATCCTTGGAAGCAACTTTAGGAGCGGATAATGTAGTCATTGATATTCAACAACTACAAAAAGACGAAGTA
AACAATATTACATATTTTGCTGAAAATGCTGCTGGTGAAGACTGGGATTTATCAGATAATGTCGGTTGGGGTCCAGACTT
TGCCGATCCATCAACCTACCTTGATATCATCAAACCATCTGTAGGAGAAAGTACTAAAACATATTTAGGGTTTGACTCAG
GGGAAGATAATGTAGCTGCTAAAAAAGTAGGTCTATATGACTACGAAAAATTGGTTACTGAGGCTGGTGATGAGACTACA
GATGTTGCTAAACGCTATGATAAATACGCTGCAGCCCAAGCTTGGTTGACAGATAGTGCTTTGATTATTCCAACTACATC
TCGTACAGGGCGTCCAATCTTGTCTAAGATGGTACCATTTACAATACCATTTGCATTGTCAGGAAATAAAGGCACAAGTG
AACCAGTCTTGTATAAATACTTGGAACTTCAAGACAAGGCAGTCACTGTAGATGAATACCAAAAAGCTCAGGAAAAATGG
ATGAAAGAAAAAGAAGAGTCTAATAAAAAGGCTCAAGAAGATCTCGCAAAACATGTGAAATAA

Domains

Predicted by InterproScan.

• Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5) (77-519)

3D structure

• AlphaFold DB: A0A6I3TKG5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiA3	Streptococcus thermophilus LMD-9	58.245	100	0.583
amiA3	Streptococcus thermophilus LMG 18311	57.943	100	0.58
amiA	Streptococcus salivarius strain HSISS4	57.943	100	0.58