Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SGGBAA2069_RS02475 Genome accession   NC_015215
Coordinates   465917..466561 (+) Length   214 a.a.
NCBI ID   WP_009853571.1    Uniprot ID   A0A060RG88
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 460917..471561
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGBAA2069_RS02455 (SGGBAA2069_c04290) - 461491..462228 (+) 738 WP_009853567.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SGGBAA2069_RS02460 (SGGBAA2069_c04300) pknB 462228..464105 (+) 1878 WP_012961536.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SGGBAA2069_RS02465 (SGGBAA2069_c04310) liaF 464216..464911 (+) 696 WP_013642738.1 cell wall-active antibiotics response protein LiaF -
  SGGBAA2069_RS02470 (SGGBAA2069_c04320) - 464908..465933 (+) 1026 WP_009853570.1 sensor histidine kinase -
  SGGBAA2069_RS02475 (SGGBAA2069_c04330) vraR 465917..466561 (+) 645 WP_009853571.1 response regulator transcription factor Regulator
  SGGBAA2069_RS02480 (SGGBAA2069_c04340) - 466680..468080 (+) 1401 WP_009853572.1 Cof-type HAD-IIB family hydrolase -
  SGGBAA2069_RS02485 (SGGBAA2069_c04350) - 468080..468436 (+) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -
  SGGBAA2069_RS02490 (SGGBAA2069_c04360) cysK 468550..469479 (-) 930 WP_013642739.1 cysteine synthase A -
  SGGBAA2069_RS02495 (SGGBAA2069_c04370) - 469583..470209 (-) 627 WP_013642740.1 YigZ family protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23939.71 Da        Isoelectric Point: 4.6633

>NTDB_id=33593 SGGBAA2069_RS02475 WP_009853571.1 465917..466561(+) (vraR) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
MTQKIKVILVDDHEMVRLGLKSFLNLQPDVEVVGEAGNGLDGINLALELKPDVVVMDLVMPEMSGVEATLKLLEEWKEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVARGELAIETEVDKKIKAHDMQPELHEDLTARERDILRLL
AKGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFKHHLVPQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=33593 SGGBAA2069_RS02475 WP_009853571.1 465917..466561(+) (vraR) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
ATGACCCAGAAAATTAAAGTTATCCTAGTTGATGACCATGAAATGGTACGTTTAGGGTTAAAAAGTTTTTTGAATTTGCA
ACCAGATGTTGAGGTGGTTGGCGAAGCTGGAAATGGTTTAGATGGTATCAATTTGGCTTTAGAATTAAAACCAGATGTGG
TTGTTATGGATTTGGTAATGCCAGAAATGAGCGGTGTCGAAGCAACATTGAAGCTTCTGGAAGAATGGAAGGAAGCTAAA
ATTCTTGTTTTAACATCTTACCTTGATAACGAAAAAATTTATCCTGTCATTGAAGCAGGTGCTAAAGGTTATATGTTAAA
AACATCTAGCGCAGCAGAAATTTTAAATGCCATTCAGAAAGTTGCACGTGGTGAGTTAGCTATTGAAACAGAAGTCGATA
AAAAAATCAAAGCTCATGATATGCAACCAGAATTGCATGAAGATTTGACAGCGCGTGAACGTGATATTTTGAGATTACTT
GCTAAAGGGTATGATAATCAAACTATTGCTGATGAGCTATTTATCTCACTAAAAACCGTCAAAACACACGTTTCAAATAT
TCTAGCTAAGTTAGAAGTTGATGACCGTACACAAGCAGTCGTTTATGCCTTTAAACATCATTTAGTACCGCAAGATGACG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A060RG88

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.427

96.262

0.505
  degU Bacillus subtilis subsp. subtilis str. 168

37.5

100

0.393

Multiple sequence alignment