Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FX998_RS04400 Genome accession   NZ_CP043227
Coordinates   880987..881643 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain Ec-050     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 875987..886643
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FX998_RS04370 (FX998_04370) yecA 877239..877904 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  FX998_RS04390 (FX998_04390) pgsA 878553..879101 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FX998_RS04395 (FX998_04395) uvrC 879158..880990 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  FX998_RS04400 (FX998_04400) letA 880987..881643 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FX998_RS26180 (FX998_04405) - 881785..881901 (+) 117 WP_001302039.1 hypothetical protein -
  FX998_RS04410 (FX998_04410) yecU 881939..882115 (+) 177 WP_000590344.1 protein YecU -
  FX998_RS04415 (FX998_04415) yecF 882102..882326 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  FX998_RS04420 (FX998_04420) sdiA 882394..883116 (-) 723 WP_001154260.1 transcriptional regulator SdiA -
  FX998_RS04425 (FX998_04425) tcyN 883346..884098 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FX998_RS04430 (FX998_04430) tcyL 884095..884763 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  FX998_RS04435 (FX998_04435) dcyD 884778..885764 (-) 987 WP_039023114.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=335850 FX998_RS04400 WP_000611328.1 880987..881643(-) (letA) [Escherichia coli strain Ec-050]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=335850 FX998_RS04400 WP_000611328.1 880987..881643(-) (letA) [Escherichia coli strain Ec-050]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment