Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FYA04_RS12240 Genome accession   NZ_CP043213
Coordinates   2467325..2467981 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O16:H48 strain CV601gfp     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2462325..2472981
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FYA04_RS12210 (FYA04_12210) yecA 2463576..2464241 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  FYA04_RS12230 (FYA04_12230) pgsA 2464891..2465439 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FYA04_RS12235 (FYA04_12235) uvrC 2465496..2467328 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  FYA04_RS12240 (FYA04_12240) letA 2467325..2467981 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FYA04_RS23460 - 2468123..2468194 (+) 72 Protein_2417 transcriptional regulator -
  FYA04_RS12245 (FYA04_12245) yecU 2468277..2468453 (+) 177 WP_000590347.1 protein YecU -
  FYA04_RS12250 (FYA04_12250) yecF 2468440..2468664 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  FYA04_RS12255 (FYA04_12255) sdiA 2468732..2469454 (-) 723 WP_001152715.1 transcriptional regulator SdiA -
  FYA04_RS12260 (FYA04_12260) tcyN 2469684..2470436 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FYA04_RS12265 (FYA04_12265) tcyL 2470433..2471101 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  FYA04_RS12270 (FYA04_12270) dcyD 2471116..2472102 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=335706 FYA04_RS12240 WP_000611335.1 2467325..2467981(-) (letA) [Escherichia coli O16:H48 strain CV601gfp]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=335706 FYA04_RS12240 WP_000611335.1 2467325..2467981(-) (letA) [Escherichia coli O16:H48 strain CV601gfp]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment