Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   SEQ_RS08310 Genome accession   NC_012471
Coordinates   1725416..1726165 (-) Length   249 a.a.
NCBI ID   WP_012679946.1    Uniprot ID   C0M6E8
Organism   Streptococcus equi subsp. equi 4047     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1720416..1731165
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SEQ_RS08295 (SEQ_1710) - 1722371..1723729 (+) 1359 WP_012679944.1 bacteriocin secretion accessory protein -
  SEQ_RS08300 (SEQ_1710a) - 1723829..1723960 (+) 132 WP_012677513.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SEQ_RS11975 - 1724082..1724912 (-) 831 WP_230197368.1 GHKL domain-containing protein -
  SEQ_RS08310 (SEQ_1712) comE/blpR 1725416..1726165 (-) 750 WP_012679946.1 response regulator transcription factor Regulator
  SEQ_RS08315 (SEQ_1713) - 1726792..1726995 (-) 204 WP_012679947.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  SEQ_RS08320 (SEQ_1714) - 1727012..1727269 (-) 258 WP_012679948.1 Blp family class II bacteriocin -
  SEQ_RS08325 (SEQ_1715) rlmD 1727590..1728957 (-) 1368 WP_012679949.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
  SEQ_RS08330 (SEQ_1716) - 1728954..1729922 (-) 969 WP_012679950.1 DNA-binding protein -
  SEQ_RS08335 (SEQ_1717) recX 1729986..1730762 (+) 777 WP_012679951.1 recombination regulator RecX -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29257.72 Da        Isoelectric Point: 8.7559

>NTDB_id=33534 SEQ_RS08310 WP_012679946.1 1725416..1726165(-) (comE/blpR) [Streptococcus equi subsp. equi 4047]
MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLLSAIKKNCGQQLFFLDIEIKNENKKGLEVARQIRQIN
PDAMIVFVTTHSEFMPLAFQYQVSALDYIDKELPQTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINHRNVVRVDKIERVVYFRNGSSCLIARSKMNSVLTT
IENLHRGDN

Nucleotide


Download         Length: 750 bp        

>NTDB_id=33534 SEQ_RS08310 WP_012679946.1 1725416..1726165(-) (comE/blpR) [Streptococcus equi subsp. equi 4047]
GTGAGAGTAGTTATTTTAGAAGATGATATGATTCAGCAGAGATATTTAGAAAAGCTCATTAAAGAGCTTGAGGTTAAGCA
CCAGCTATTATTTCAAGGACTTGACTGTTTTGGAAGGCCTCATCAGCTATTAAGTGCTATCAAGAAGAACTGTGGTCAGC
AGCTATTCTTTTTAGATATTGAGATAAAAAATGAGAACAAAAAAGGGCTTGAGGTTGCTAGGCAAATTCGTCAGATAAAT
CCAGATGCGATGATTGTTTTTGTAACGACTCACTCGGAATTTATGCCCTTGGCTTTTCAGTATCAGGTATCTGCTTTGGA
CTATATCGATAAAGAGCTGCCTCAAACTGAGTTTGTTCAACGGGTAGAGACTGCTTTATTATATGCTGTGCGGCAAAATA
GTGAAACGATAGCGGAAAGTGCTTTTTATTTTACATCTCGTTATGCTCAGGTACAGGTGCCTTTTAATGATATCCTGTAT
ATTGAGACATCGTCACGAGCGCATCGTGTCAATTTGTATACAAAAAAGGAGAGAATGCAATTTACGGGGACTTTGACGGA
TATTTTGAAGCAAGAGTCTCGTTTTTTGCAATGTCATCGTTCTTTTTTGATTAATCATAGGAATGTCGTTAGGGTAGATA
AGATTGAGCGAGTGGTTTATTTTCGAAATGGCTCTAGCTGCTTAATTGCTCGTAGTAAAATGAACAGTGTTTTAACAACA
ATTGAGAACCTACATAGAGGAGATAATTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0M6E8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.209

100

0.522
  comE/comE1 Streptococcus equinus JB1

40.167

95.984

0.386

Multiple sequence alignment