Detailed information NTG0335128

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: EQI27_RS12985
• Genome accession: NZ_CP035163
• Coordinates: 2509942..2512272 (-)
• Length: 776 a.a.
• NCBI ID: WP_074794436.1
• Uniprot ID: A0A8E0SBN0
• Organism: Bacillus subtilis strain SRCM103923
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2504942..2517272

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQI27_RS12950 (EQI27_12950)	yqxA	2505282..2505619 (-)	338	Protein_2509	YqxA family protein	-
EQI27_RS12955 (EQI27_12955)	spoIIP	2505636..2506841 (-)	1206	WP_014477383.1	spore autolysin SpoIIP	-
EQI27_RS12960 (EQI27_12960)	gpr	2506904..2508010 (-)	1107	WP_109962781.1	GPR endopeptidase	-
EQI27_RS12965 (EQI27_12965)	rpsT	2508214..2508480 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
EQI27_RS12970 (EQI27_12970)	holA	2508495..2509538 (-)	1044	WP_015714286.1	DNA polymerase III subunit delta	-
EQI27_RS12975 (EQI27_12975)	-	2509578..2509727 (-)	150	WP_003229985.1	hypothetical protein	-
EQI27_RS12980 (EQI27_12980)	yqzM	2509768..2509902 (+)	135	WP_003229983.1	YqzM family protein	-
EQI27_RS12985 (EQI27_12985)	comEC	2509942..2512272 (-)	2331	WP_074794436.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EQI27_RS12990 (EQI27_12990)	comEB	2512269..2512838 (-)	570	WP_015714288.1	ComE operon protein 2	-
EQI27_RS12995 (EQI27_12995)	comEA	2512905..2513522 (-)	618	WP_004398514.1	competence protein ComEA	Machinery gene
EQI27_RS13000 (EQI27_13000)	comER	2513606..2514427 (+)	822	WP_004398597.1	late competence protein ComER	-
EQI27_RS13005 (EQI27_13005)	yqeM	2514493..2515236 (-)	744	WP_003229973.1	class I SAM-dependent methyltransferase	-
EQI27_RS13010 (EQI27_13010)	rsfS	2515233..2515589 (-)	357	WP_003229971.1	ribosome silencing factor	-
EQI27_RS13015 (EQI27_13015)	yqeK	2515607..2516166 (-)	560	Protein_2522	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
EQI27_RS13020 (EQI27_13020)	nadD	2516156..2516725 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
EQI27_RS13025 (EQI27_13025)	yhbY	2516737..2517027 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86642.27 Da
• Isoelectric Point: 7.2477

>NTDB_id=335128 EQI27_RS12985 WP_074794436.1 2509942..2512272(-) (comEC) [Bacillus subtilis strain SRCM103923]
MMNSRLLLPMAAASATAGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDTIPKIDGDRMSMVVKTPDKEKWAAAYRILSAGEKEQLLYIEPGMSCELTGTLEEPNHATVPGAFDYNEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHTISFTNSLLPPDSAGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIMIRLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMSGVYLAGSLVKWRVHSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFQQVKTSLGQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWTNRLITNIADVDVFTIMIAHPAPVLLFLFTVAIILLLMAIEKRSLSQLMITGG
ICCTVMFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKVLIPFLTAKG
IKQLDALILTHADQDHIGEAETLLKHHKVKRLVIPKGFVSEPKDEKVLQTAREEGVTIEEVKRGDVLQIKDLQFHVLSPE
TPDPASKNNSSLVLWMETGVLSWILTGDLEKEGEQEVMDVFPNIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKN
NRYHHPHQKVLQLLQRHSIRVLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=335128 EQI27_RS12985 WP_074794436.1 2509942..2512272(-) (comEC) [Bacillus subtilis strain SRCM103923]
GTGATGAATTCGCGTTTGTTATTGCCTATGGCGGCAGCTTCGGCAACGGCTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATTTTAATCAAAACGAGGCACGCTTTTCTTATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACCTATCAATTC
AAGGCAGTGATTGACACTATTCCCAAAATTGACGGCGACCGTATGTCTATGGTGGTTAAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCTGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACATTGGAAGAACCGAATCACGCAACTGTGCCGGGAGCATTTGATTATAACGAGTATCTTTATCGGCAGCATATT
CATTGGAACTACTCTGTCACGTCTATTCAAAACTGCAGCGAACCTGAAAATTTTAAGTACAAGGTGCTCAGCTTGAGAAA
ACATACCATATCATTCACAAACAGCCTTTTGCCTCCTGATTCGGCAGGGATTGTACAGGCACTTACAGTTGGTGACAGAT
TTTATGTGGAGGACGAAGTGCTTACCGCGTATCAAAAGCTTGGTGTTGTCCATCTTTTGGCAATATCAGGACTCCACGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATGATTCGCCTTGGTATAACTAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTCCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGCCTTGTCAAATGGCGTGTCCACTCTGCAACTGCAATTTGCCTTTCATACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCAGCA
GGTTAAAACCTCCTTGGGACAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTTCTATATCATT
TTCATCAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGCTGGTTTGATTTATTGATAAGCTG
GACCAATAGGCTAATCACAAACATTGCAGATGTTGATGTGTTCACGATTATGATCGCACATCCTGCACCTGTTTTGCTTT
TTTTATTCACGGTTGCGATCATCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGATAACCGGCGGC
ATTTGCTGCACGGTGATGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCATCAGCGGGGTCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGGTGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAACAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGACTCTGCTGAAGCATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGACAGCCAGAGAAG
AGGGAGTGACAATTGAAGAGGTGAAGCGAGGCGATGTATTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCTGAA
ACACCTGATCCGGCAAGCAAAAATAATTCCTCTCTCGTTCTGTGGATGGAGACGGGCGTTCTGAGCTGGATTTTGACGGG
TGATCTGGAGAAAGAAGGGGAACAGGAGGTGATGGACGTGTTTCCAAATATTAAAGCAGATGTCTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCATCCAACAGCTTCAGCCGAAAACGGCCATTATCTCAGCCGGGAAAAAC
AATCGGTACCATCATCCTCATCAAAAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGATCAAAA
CGGAACGATCCAATATAGATACAAAAACAGAGTTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

• Competence protein (Competence) (208-469)

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	97.809	100	0.978