Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   SZO_RS04725 Genome accession   NC_012470
Coordinates   1000859..1002088 (+) Length   409 a.a.
NCBI ID   WP_012677889.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 970548..1008347 1000859..1002088 within 0


Gene organization within MGE regions


Location: 970548..1008347
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SZO_RS04595 (SZO_08670) - 970548..971147 (+) 600 WP_012677865.1 glycoside hydrolase family 73 protein -
  SZO_RS04600 (SZO_08680) - 971707..971904 (+) 198 WP_012677866.1 helix-turn-helix transcriptional regulator -
  SZO_RS04605 (SZO_08690) - 971909..972352 (+) 444 WP_228274887.1 hypothetical protein -
  SZO_RS04610 - 972456..972662 (+) 207 WP_012515719.1 hypothetical protein -
  SZO_RS10790 - 972744..972957 (+) 214 Protein_875 conjugal transfer protein TraA -
  SZO_RS04615 (SZO_08700) - 973071..974429 (+) 1359 WP_012677868.1 SLC13 family permease -
  SZO_RS04620 (SZO_08710) - 974875..975585 (+) 711 WP_012677869.1 glycoside hydrolase family 73 protein -
  SZO_RS04625 (SZO_08720) - 975799..976179 (+) 381 WP_012677870.1 DUF1149 family protein -
  SZO_RS04630 (SZO_08730) - 976179..977027 (+) 849 WP_012677871.1 DegV family protein -
  SZO_RS04635 (SZO_08740) - 977131..978342 (+) 1212 WP_041790695.1 CCA tRNA nucleotidyltransferase -
  SZO_RS04640 (SZO_08750) - 978335..980203 (+) 1869 WP_012677873.1 ABC-F family ATP-binding cassette domain-containing protein -
  SZO_RS04645 (SZO_08760) - 980308..982053 (+) 1746 WP_012677874.1 ABC transporter ATP-binding protein -
  SZO_RS04650 (SZO_08770) - 982053..983825 (+) 1773 WP_012677875.1 ABC transporter ATP-binding protein -
  SZO_RS04655 (SZO_08780) gdhA 983966..985315 (+) 1350 WP_012677876.1 NADP-specific glutamate dehydrogenase -
  SZO_RS04660 (SZO_08790) - 985445..985855 (+) 411 WP_012677877.1 peptide deformylase -
  SZO_RS04665 (SZO_08800) - 986047..988053 (-) 2007 WP_012677878.1 surface-anchored 5'-nucleotidase -
  SZO_RS04670 (SZO_08810) - 988502..990223 (+) 1722 WP_012677879.1 ABC transporter ATP-binding protein -
  SZO_RS04675 (SZO_08820) - 990225..991976 (+) 1752 WP_012677880.1 ABC transporter ATP-binding protein -
  SZO_RS04680 (SZO_08830) mvk 992507..993385 (+) 879 WP_012677881.1 mevalonate kinase -
  SZO_RS04685 (SZO_08840) mvaD 993367..994311 (+) 945 WP_012677882.1 diphosphomevalonate decarboxylase -
  SZO_RS04690 (SZO_08850) - 994304..995302 (+) 999 WP_041790422.1 phosphomevalonate kinase -
  SZO_RS04695 (SZO_08860) fni 995305..996297 (+) 993 WP_012677884.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  SZO_RS04700 (SZO_08870) - 996583..997866 (-) 1284 WP_041790698.1 hydroxymethylglutaryl-CoA reductase, degradative -
  SZO_RS04705 (SZO_08880) - 997853..999031 (-) 1179 WP_012677886.1 hydroxymethylglutaryl-CoA synthase -
  SZO_RS04710 (SZO_08890) - 999216..1000055 (+) 840 WP_012677887.1 thymidylate synthase -
  SZO_RS04715 (SZO_08900) - 1000136..1000633 (+) 498 WP_012677888.1 dihydrofolate reductase -
  SZO_RS10630 (SZO_08910) - 1000653..1000823 (+) 171 WP_012515696.1 hypothetical protein -
  SZO_RS04725 (SZO_08920) clpX 1000859..1002088 (+) 1230 WP_012677889.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  SZO_RS04730 (SZO_08930) yihA 1002098..1002697 (+) 600 WP_012677890.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  SZO_RS04735 (SZO_08940) hupY 1003062..1006064 (+) 3003 WP_012677891.1 leucine-rich repeat adhesin HupY/LrrG -
  SZO_RS04740 (SZO_08950) - 1006254..1008347 (-) 2094 WP_012677892.1 AAA family ATPase -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45197.77 Da        Isoelectric Point: 4.5726

>NTDB_id=33469 SZO_RS04725 WP_012677889.1 1000859..1002088(+) (clpX) [Streptococcus equi subsp. zooepidemicus]
MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLEILNQYVIGQER
AKRALSVAVYNHYKRISFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKIDDNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRI
LTEPRNALVKQYQALLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVIKVRITKEAVEG
QSKPILEIA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=33469 SZO_RS04725 WP_012677889.1 1000859..1002088(+) (clpX) [Streptococcus equi subsp. zooepidemicus]
ATGGCAGGAAATCGTAGTAACGATATTAAGGTTCATTGCTCGTTTTGCGGCAAGAGCCAAGACGAAGTGAAAAAAATTAT
TGCAGGTAATAACGTCTTTATTTGTAACGAATGTGTTGCCTTATCACAAGAAATCATCAAGGAAGAATTGGCAGAAGAGG
TTCTCGCTGATCTGACTGAGGTACCAAAGCCAAAAGAGCTGCTTGAGATTTTAAATCAATACGTCATTGGGCAGGAGCGT
GCTAAGAGAGCCTTATCAGTTGCAGTTTACAACCACTACAAGAGGATTTCATTTACTGAGAGTCGTGACGATGATGATGT
GGATTTGCAGAAGTCCAATATTCTGATGATTGGACCAACAGGCTCAGGAAAGACCTTTTTGGCACAGACCCTAGCTAAGA
GTTTGAATGTTCCGTTTGCTATTGCTGATGCAACCTCTTTGACTGAAGCAGGCTATGTCGGAGAGGATGTGGAAAATATC
CTTCTGAAATTAATTCAAGCCGCTGATTACAATGTTGAACGTGCAGAGCGTGGCATTATTTATGTTGACGAAATTGATAA
AATCGCTAAAAAAGGTGAGAATGTCTCCATTACTCGTGATGTATCAGGAGAGGGTGTCCAACAAGCCTTGCTAAAAATCA
TTGAAGGAACGGTTGCCAGTGTTCCACCACAGGGTGGTCGTAAGCACCCAAACCAAGAGATGATACAGATTGATACCAAA
AATATCTTATTTATCGTCGGAGGCGCTTTTGATGGTATCGAAGAAATTGTCAAGCAGCGCTTGGGAGAAAAGATCATTGG
CTTTGGGCAAAATAGTCGAAAGATTGATGACAATGCTTCCTATATGCAGGAGATCATTGCTGAGGATATTCAAAAATTTG
GTCTGATTCCCGAATTTATTGGACGCTTGCCTGTTGTAGCAGCGCTTGAGCAGCTTAATACTGAGGATTTGATTCGTATT
TTAACAGAGCCTAGAAATGCCCTTGTGAAGCAATATCAAGCCTTATTGTCATATGATGGCGTAGAGCTTGAGTTTGAAAA
GGGGGCTCTGGAGGCTATTGCAGGTAGGGCTATTGAGCGCAAGACTGGTGCGCGTGGTCTGAGGTCTATTATTGAAGAAA
CCATGCTGGATATCATGTTTGAGGTGCCAAGCCAAGAGGAAGTAATCAAGGTACGCATTACTAAGGAAGCTGTCGAAGGT
CAATCAAAGCCTATTTTAGAGATAGCCTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-389)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

88.753

100

0.888
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.853

98.044

0.577

Multiple sequence alignment