Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FYA18_RS03665 Genome accession   NZ_CP043185
Coordinates   726069..726725 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O16:H48 strain PG20180171     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 721069..731725
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FYA18_RS03635 (FYA18_03635) yecA 722320..722985 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  FYA18_RS03655 (FYA18_03655) pgsA 723635..724183 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FYA18_RS03660 (FYA18_03660) uvrC 724240..726072 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  FYA18_RS03665 (FYA18_03665) letA 726069..726725 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FYA18_RS23140 - 726867..726938 (+) 72 Protein_728 transcriptional regulator -
  FYA18_RS03670 (FYA18_03670) yecU 727021..727197 (+) 177 WP_000590347.1 protein YecU -
  FYA18_RS03675 (FYA18_03675) yecF 727184..727408 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  FYA18_RS03680 (FYA18_03680) sdiA 727476..728198 (-) 723 WP_001152715.1 transcriptional regulator SdiA -
  FYA18_RS03685 (FYA18_03685) tcyN 728428..729180 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FYA18_RS03690 (FYA18_03690) tcyL 729177..729845 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  FYA18_RS03695 (FYA18_03695) dcyD 729860..730846 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=334557 FYA18_RS03665 WP_000611335.1 726069..726725(-) (letA) [Escherichia coli O16:H48 strain PG20180171]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=334557 FYA18_RS03665 WP_000611335.1 726069..726725(-) (letA) [Escherichia coli O16:H48 strain PG20180171]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment