Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FYA20_RS01810 Genome accession   NZ_CP043181
Coordinates   345727..346383 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli O2:H6 strain PG20180057     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 340727..351383
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FYA20_RS01780 (FYA20_01780) yecA 341979..342644 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  FYA20_RS01800 (FYA20_01800) pgsA 343293..343841 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FYA20_RS01805 (FYA20_01805) uvrC 343898..345730 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  FYA20_RS01810 (FYA20_01810) letA 345727..346383 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FYA20_RS01815 (FYA20_01815) yecU 346679..346855 (+) 177 WP_001307856.1 protein YecU -
  FYA20_RS01820 (FYA20_01820) yecF 346842..347066 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  FYA20_RS01825 (FYA20_01825) sdiA 347134..347856 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  FYA20_RS01830 (FYA20_01830) tcyN 348086..348838 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FYA20_RS01835 (FYA20_01835) tcyL 348835..349503 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  FYA20_RS01840 (FYA20_01840) dcyD 349518..350504 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=334385 FYA20_RS01810 WP_000611328.1 345727..346383(-) (letA) [Escherichia coli O2:H6 strain PG20180057]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=334385 FYA20_RS01810 WP_000611328.1 345727..346383(-) (letA) [Escherichia coli O2:H6 strain PG20180057]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482