Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   EMO93_RS10885 Genome accession   NZ_CP035003
Coordinates   2164250..2164819 (+) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus strain PCFA-221     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2159250..2169819
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EMO93_RS10860 cysE 2160462..2161109 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  EMO93_RS10865 cysS 2161093..2162493 (+) 1401 WP_000631961.1 cysteine--tRNA ligase -
  EMO93_RS10870 - 2162486..2162890 (+) 405 WP_000370181.1 Mini-ribonuclease 3 -
  EMO93_RS10875 rlmB 2162898..2163644 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  EMO93_RS10880 - 2163644..2164168 (+) 525 WP_000664738.1 NYN domain-containing protein -
  EMO93_RS10885 sigH 2164250..2164819 (+) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  EMO93_RS10890 rpmG 2164934..2165077 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  EMO93_RS10895 secE 2165133..2165315 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  EMO93_RS10900 nusG 2165328..2165876 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  EMO93_RS10905 rplK 2166057..2166479 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  EMO93_RS10910 rplA 2166687..2167379 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  EMO93_RS10920 rplJ 2167651..2168151 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  EMO93_RS10925 rplL 2168194..2168562 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  EMO93_RS10930 - 2168737..2169345 (+) 609 WP_000020293.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=333902 EMO93_RS10885 WP_000872879.1 2164250..2164819(+) (sigH) [Staphylococcus aureus strain PCFA-221]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=333902 EMO93_RS10885 WP_000872879.1 2164250..2164819(+) (sigH) [Staphylococcus aureus strain PCFA-221]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment