Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   FWK58_RS02340 Genome accession   NZ_CP042991
Coordinates   496585..497292 (+) Length   235 a.a.
NCBI ID   WP_075294057.1    Uniprot ID   A0A9Q6Z032
Organism   Histophilus somni strain UOC-KLM-ATR-012     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 491585..502292
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FWK58_RS02300 (FWK58_02300) - 491877..492119 (+) 243 WP_011608610.1 hypothetical protein -
  FWK58_RS02305 (FWK58_02305) - 492158..492892 (+) 735 WP_075294059.1 4'-phosphopantetheinyl transferase superfamily protein -
  FWK58_RS02315 (FWK58_02315) gltX 493231..494673 (-) 1443 WP_075294058.1 glutamate--tRNA ligase -
  FWK58_RS02335 (FWK58_02335) pilC 495368..496588 (+) 1221 WP_012341581.1 type II secretion system F family protein Machinery gene
  FWK58_RS02340 (FWK58_02340) pilD 496585..497292 (+) 708 WP_075294057.1 A24 family peptidase Machinery gene
  FWK58_RS02345 (FWK58_02345) coaE 497312..497959 (+) 648 WP_075294056.1 dephospho-CoA kinase -
  FWK58_RS02350 (FWK58_02350) yacG 497956..498150 (+) 195 WP_075294055.1 DNA gyrase inhibitor YacG -
  FWK58_RS02355 (FWK58_02355) - 498555..499931 (+) 1377 WP_075294054.1 sodium:alanine symporter family protein -
  FWK58_RS02360 (FWK58_02360) raiA 500167..500484 (+) 318 WP_012341586.1 ribosome-associated translation inhibitor RaiA -
  FWK58_RS02365 (FWK58_02365) hpt 500688..501227 (+) 540 WP_011608620.1 hypoxanthine phosphoribosyltransferase -
  FWK58_RS02370 (FWK58_02370) sodA 501356..501985 (-) 630 WP_075294053.1 superoxide dismutase [Mn] -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27023.51 Da        Isoelectric Point: 8.1958

>NTDB_id=333787 FWK58_RS02340 WP_075294057.1 496585..497292(+) (pilD) [Histophilus somni strain UOC-KLM-ATR-012]
MIYLAYMLFGGLCGLWVYLYVRQFSAQINKQVYSTFCEIFPENAPHLMPMSILRRKKCGHFSMYFLCGGLWCNICLNFPQ
NIYVGLWLACCSYLIFCLVLVDWLYQLVSQTLCQALFILGLLGAYQGISPLTLEQSLVGSLSGFSVFYLIYIVAKLFYRY
EALGRGDYWLMLGLGSFISWTKLPLLIFLACLTGLIYVVFNARDKKTIFIPFAPFLCLSTIIVYLLNFLREDILP

Nucleotide


Download         Length: 708 bp        

>NTDB_id=333787 FWK58_RS02340 WP_075294057.1 496585..497292(+) (pilD) [Histophilus somni strain UOC-KLM-ATR-012]
ATGATTTATCTAGCTTATATGTTGTTTGGTGGGCTTTGTGGCTTATGGGTTTACCTTTATGTCAGGCAATTTTCTGCTCA
GATTAATAAACAAGTTTACTCGACTTTTTGCGAAATTTTCCCCGAAAATGCACCGCACTTGATGCCTATGTCTATCTTAC
GACGGAAAAAGTGCGGTCATTTTTCTATGTATTTTTTGTGTGGTGGCCTTTGGTGTAATATATGTTTAAATTTCCCACAA
AATATTTATGTTGGTTTATGGTTAGCATGTTGCAGTTATTTAATTTTTTGCCTTGTTTTAGTGGATTGGCTATACCAACT
CGTTTCACAAACCTTATGCCAAGCCCTATTTATTTTAGGGTTATTGGGTGCTTATCAAGGTATTAGCCCATTGACTTTGG
AGCAGTCTTTAGTTGGTAGCTTATCAGGCTTTTCGGTTTTTTATCTTATTTACATTGTTGCAAAATTATTCTATCGTTAT
GAAGCTTTAGGACGTGGCGATTATTGGTTAATGTTAGGGTTAGGGAGCTTTATATCTTGGACAAAATTACCGTTGCTCAT
TTTTCTTGCCTGCCTCACAGGATTAATATATGTCGTTTTTAATGCAAGAGACAAAAAAACAATATTTATTCCTTTTGCCC
CGTTCTTATGTCTCTCAACCATTATCGTATACTTGCTTAATTTTCTAAGGGAGGATATTCTTCCTTAA

Domains

Predicted by InterProScan.

Type IV leader peptidase family (Peptidase_A24)

(94-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9Q6Z032

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

39.13

97.872

0.383
  pilD Haemophilus influenzae Rd KW20

36.957

97.872

0.362