Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   FWK50_RS02315 Genome accession   NZ_CP042989
Coordinates   496548..497255 (+) Length   235 a.a.
NCBI ID   WP_075294057.1    Uniprot ID   A0A9Q6Z032
Organism   Histophilus somni strain UOC-KLM-ATR-010     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 491548..502255
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FWK50_RS02275 (FWK50_02275) - 491840..492082 (+) 243 WP_011608610.1 hypothetical protein -
  FWK50_RS02280 (FWK50_02280) - 492121..492855 (+) 735 WP_075294059.1 4'-phosphopantetheinyl transferase superfamily protein -
  FWK50_RS02290 (FWK50_02290) gltX 493194..494636 (-) 1443 WP_075294058.1 glutamate--tRNA ligase -
  FWK50_RS02310 (FWK50_02310) pilC 495331..496551 (+) 1221 WP_012341581.1 type II secretion system F family protein Machinery gene
  FWK50_RS02315 (FWK50_02315) pilD 496548..497255 (+) 708 WP_075294057.1 A24 family peptidase Machinery gene
  FWK50_RS02320 (FWK50_02320) coaE 497275..497922 (+) 648 WP_075294056.1 dephospho-CoA kinase -
  FWK50_RS02325 (FWK50_02325) yacG 497919..498113 (+) 195 WP_075294055.1 DNA gyrase inhibitor YacG -
  FWK50_RS02330 (FWK50_02330) - 498518..499894 (+) 1377 WP_075294054.1 sodium:alanine symporter family protein -
  FWK50_RS02335 (FWK50_02335) raiA 500130..500447 (+) 318 WP_012341586.1 ribosome-associated translation inhibitor RaiA -
  FWK50_RS02340 (FWK50_02340) hpt 500651..501190 (+) 540 WP_011608620.1 hypoxanthine phosphoribosyltransferase -
  FWK50_RS02345 (FWK50_02345) sodA 501319..501948 (-) 630 WP_075294053.1 superoxide dismutase [Mn] -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27023.51 Da        Isoelectric Point: 8.1958

>NTDB_id=333675 FWK50_RS02315 WP_075294057.1 496548..497255(+) (pilD) [Histophilus somni strain UOC-KLM-ATR-010]
MIYLAYMLFGGLCGLWVYLYVRQFSAQINKQVYSTFCEIFPENAPHLMPMSILRRKKCGHFSMYFLCGGLWCNICLNFPQ
NIYVGLWLACCSYLIFCLVLVDWLYQLVSQTLCQALFILGLLGAYQGISPLTLEQSLVGSLSGFSVFYLIYIVAKLFYRY
EALGRGDYWLMLGLGSFISWTKLPLLIFLACLTGLIYVVFNARDKKTIFIPFAPFLCLSTIIVYLLNFLREDILP

Nucleotide


Download         Length: 708 bp        

>NTDB_id=333675 FWK50_RS02315 WP_075294057.1 496548..497255(+) (pilD) [Histophilus somni strain UOC-KLM-ATR-010]
ATGATTTATCTAGCTTATATGTTGTTTGGTGGGCTTTGTGGCTTATGGGTTTACCTTTATGTCAGGCAATTTTCTGCTCA
GATTAATAAACAAGTTTACTCGACTTTTTGCGAAATTTTCCCCGAAAATGCACCGCACTTGATGCCTATGTCTATCTTAC
GACGGAAAAAGTGCGGTCATTTTTCTATGTATTTTTTGTGTGGTGGCCTTTGGTGTAATATATGTTTAAATTTCCCACAA
AATATTTATGTTGGTTTATGGTTAGCATGTTGCAGTTATTTAATTTTTTGCCTTGTTTTAGTGGATTGGCTATACCAACT
CGTTTCACAAACCTTATGCCAAGCCCTATTTATTTTAGGGTTATTGGGTGCTTATCAAGGTATTAGCCCATTGACTTTGG
AGCAGTCTTTAGTTGGTAGCTTATCAGGCTTTTCGGTTTTTTATCTTATTTACATTGTTGCAAAATTATTCTATCGTTAT
GAAGCTTTAGGACGTGGCGATTATTGGTTAATGTTAGGGTTAGGGAGCTTTATATCTTGGACAAAATTACCGTTGCTCAT
TTTTCTTGCCTGCCTCACAGGATTAATATATGTCGTTTTTAATGCAAGAGACAAAAAAACAATATTTATTCCTTTTGCCC
CGTTCTTATGTCTCTCAACCATTATCGTATACTTGCTTAATTTTCTAAGGGAGGATATTCTTCCTTAA

Domains

Predicted by InterProScan.

Type IV leader peptidase family (Peptidase_A24)

(94-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9Q6Z032

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

39.13

97.872

0.383
  pilD Haemophilus influenzae Rd KW20

36.957

97.872

0.362