Detailed information NTG0333648

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: FWK49_RS07850
• Genome accession: NZ_CP042988
• Coordinates: 1746518..1747762 (+)
• Length: 414 a.a.
• NCBI ID: WP_075293630.1
• Uniprot ID: A0A9Q7E5Q0
• Organism: Histophilus somni strain UOC-KLM-ATR-09
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1741518..1752762

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FWK49_RS07835 (FWK49_07835)	pilB	1742763..1744178 (-)	1416	WP_232451458.1	GspE/PulE family protein	Machinery gene
FWK49_RS07840 (FWK49_07840)	tig	1744537..1745835 (+)	1299	WP_075293628.1	trigger factor	-
FWK49_RS07845 (FWK49_07845)	clpP	1745921..1746502 (+)	582	WP_075293629.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	-
FWK49_RS07850 (FWK49_07850)	clpX	1746518..1747762 (+)	1245	WP_075293630.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
FWK49_RS07855 (FWK49_07855)	ilvD	1748161..1749996 (-)	1836	WP_012341084.1	dihydroxy-acid dehydratase	-
FWK49_RS07860 (FWK49_07860)	-	1750169..1751719 (-)	1551	WP_136122097.1	exopolyphosphatase	-

Sequence

Protein

• Length: 414 a.a.
• Molecular weight: 46039.80 Da
• Isoelectric Point: 4.5662

>NTDB_id=333648 FWK49_RS07850 WP_075293630.1 1746518..1747762(+) (clpX) [Histophilus somni strain UOC-KLM-ATR-09]
MTKEKELHCSFCGKEQKEVDKLIAGTSGYICNECIELCHDMLANADDIEEIDEEFQEEEPKLPTPHEIRAHLDDYVIGQD
YAKKVLAVAVYNHYKRLRSEKNTSEVELGKSNILLIGPTGSGKTLLAQTLARMLNVPFAMADATTLTEAGYVGEDVENVL
QKLLQNCDYDIEKAQQGIIYIDEIDKITRKSENPSITRDVSGEGVQQALLKLVEGTVASIPPQGGRKHPQQEMLRVDTSK
ILFICGGAFAGLDKIIEKRTNTGGKGIGFGADVRIDEEKVSLTELFKQVEPDDLMKFGLIPEFIGRLPVIAPLSELDEEA
LVKILTEPKNALTKQYQVLFSLENIELEFTQEALIAMAKKALARKTGARGLRSIVETLLLDTMYDLPSIENLQKVIVEEE
TVTENKVPVLKFNS

Nucleotide

• Length: 1245 bp

>NTDB_id=333648 FWK49_RS07850 WP_075293630.1 1746518..1747762(+) (clpX) [Histophilus somni strain UOC-KLM-ATR-09]
ATGACAAAAGAAAAAGAATTACATTGCTCTTTTTGTGGTAAGGAACAAAAAGAAGTAGATAAATTAATTGCAGGCACATC
CGGTTATATTTGTAATGAGTGTATTGAATTATGTCATGACATGTTAGCTAATGCGGATGACATCGAAGAAATTGATGAAG
AATTTCAAGAGGAAGAGCCTAAATTACCGACACCACATGAAATTCGTGCACATTTAGATGATTATGTCATAGGCCAAGAT
TATGCTAAAAAAGTATTAGCTGTGGCGGTGTATAATCATTATAAACGTTTACGTAGCGAAAAAAATACTTCTGAGGTTGA
ATTGGGCAAAAGTAATATTTTGCTTATCGGCCCGACAGGCAGTGGCAAGACTTTATTGGCACAAACGTTAGCTCGTATGC
TCAATGTTCCCTTTGCAATGGCAGATGCAACAACTTTAACTGAAGCGGGATATGTTGGTGAAGATGTTGAAAATGTCTTG
CAAAAATTATTACAAAATTGTGATTATGATATAGAGAAAGCTCAACAAGGTATTATCTATATTGATGAAATTGATAAGAT
TACACGTAAGTCTGAAAATCCTTCTATTACTCGTGATGTATCAGGCGAAGGTGTGCAGCAGGCTTTACTAAAATTAGTTG
AAGGAACGGTAGCTTCTATTCCTCCACAAGGCGGACGAAAGCATCCTCAACAAGAAATGTTGCGTGTGGACACCTCTAAG
ATTTTATTTATTTGTGGCGGTGCTTTTGCCGGTTTAGATAAAATTATTGAGAAAAGAACGAATACCGGTGGCAAAGGTAT
TGGTTTTGGTGCTGATGTTCGTATTGATGAAGAGAAAGTCAGTTTAACCGAATTATTTAAGCAAGTTGAACCTGATGATT
TAATGAAATTTGGCTTAATACCGGAGTTTATCGGTCGTTTACCTGTTATCGCACCTTTAAGCGAACTGGATGAGGAGGCT
TTGGTAAAAATTTTAACTGAGCCGAAAAATGCCCTAACTAAGCAATATCAAGTTTTATTCAGCTTAGAAAATATTGAATT
AGAATTTACCCAAGAAGCATTGATTGCAATGGCGAAAAAAGCACTAGCTCGTAAAACAGGTGCCAGAGGTTTGCGATCTA
TTGTTGAAACCCTATTGCTTGATACTATGTATGATCTCCCTTCTATTGAAAACTTACAGAAAGTTATAGTGGAAGAAGAA
ACAGTCACCGAAAATAAAGTGCCAGTATTGAAGTTCAATAGTTAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (316-393)

• ClpX C4-type zinc finger (zf-C4_ClpX) (7-43)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-310)

3D structure

• AlphaFold DB: A0A9Q7E5Q0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.135	100	0.594
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	54.321	97.826	0.531