Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   FWK49_RS03500 Genome accession   NZ_CP042988
Coordinates   766538..767323 (-) Length   261 a.a.
NCBI ID   WP_012340257.1    Uniprot ID   A0A9Q7E7G6
Organism   Histophilus somni strain UOC-KLM-ATR-09     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 761538..772323
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FWK49_RS03470 (FWK49_03470) - 761658..762521 (-) 864 WP_075293727.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  FWK49_RS03475 (FWK49_03475) aroB 762528..763616 (-) 1089 WP_075293728.1 3-dehydroquinate synthase -
  FWK49_RS03480 (FWK49_03480) aroK 763636..764163 (-) 528 WP_012340254.1 shikimate kinase AroK -
  FWK49_RS03485 (FWK49_03485) comE 764345..765478 (-) 1134 WP_012340255.1 type IV pilus secretin PilQ Machinery gene
  FWK49_RS03490 (FWK49_03490) - 765494..765991 (-) 498 WP_011609266.1 hypothetical protein -
  FWK49_RS03495 (FWK49_03495) - 765995..766534 (-) 540 WP_012340256.1 PilN domain-containing protein -
  FWK49_RS03500 (FWK49_03500) comA 766538..767323 (-) 786 WP_012340257.1 hypothetical protein Machinery gene
  FWK49_RS03505 (FWK49_03505) - 767448..769988 (+) 2541 WP_075293729.1 penicillin-binding protein 1A -
  FWK49_RS03510 (FWK49_03510) - 770048..770893 (+) 846 WP_075293730.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -

Sequence

Protein


Download         Length: 261 a.a.        Molecular weight: 31292.78 Da        Isoelectric Point: 7.1316

>NTDB_id=333627 FWK49_RS03500 WP_012340257.1 766538..767323(-) (comA) [Histophilus somni strain UOC-KLM-ATR-09]
MRPNKKTANILQIGIHRQDEQWQFLWFDEQKQPHFLTKNDNPPLKLSDLTPQFAKNICTWIACLPNQHVWVKTIILTQKL
NEQECQQQCNLIIENELPTDFDDIWYDYQYKELTQGAKLAIYVVRKQTAQNYVHRFFPIKINTLDCLSNSLLRAFHYFHP
QKEKMETLYLYQDRNGCIAIQEIGQQTIVLQKNDKNITALYQEFCQRFNCQPQHVWCYCEKNEQQNITHKWNIINTELPF
IALGNALWGRHELYQITELKE

Nucleotide


Download         Length: 786 bp        

>NTDB_id=333627 FWK49_RS03500 WP_012340257.1 766538..767323(-) (comA) [Histophilus somni strain UOC-KLM-ATR-09]
ATGAGACCTAACAAAAAAACAGCAAATATTTTACAAATTGGTATTCATAGACAAGATGAACAATGGCAATTCCTCTGGTT
TGATGAACAAAAACAACCGCACTTTTTAACTAAAAACGATAATCCCCCTCTTAAACTATCTGATTTGACACCACAATTCG
CAAAGAATATCTGCACATGGATAGCCTGTTTACCCAATCAGCACGTCTGGGTAAAAACAATCATATTGACGCAAAAGTTA
AATGAGCAAGAATGCCAACAACAATGTAACTTAATCATAGAAAATGAATTGCCGACAGATTTCGATGATATTTGGTACGA
CTACCAATATAAAGAATTAACACAAGGTGCAAAACTGGCTATCTACGTTGTTAGAAAACAAACAGCTCAAAATTATGTGC
ATCGTTTTTTCCCTATAAAAATTAATACATTAGATTGCTTAAGTAATAGCCTACTACGAGCATTCCATTATTTTCACCCC
CAAAAAGAAAAGATGGAAACATTATATTTATATCAGGATCGTAACGGCTGTATAGCAATACAAGAAATCGGACAACAAAC
CATCGTTCTACAAAAAAATGACAAAAATATTACCGCACTTTATCAAGAATTCTGCCAACGTTTTAACTGCCAACCTCAAC
ACGTTTGGTGCTATTGTGAAAAAAATGAACAACAAAATATCACTCATAAATGGAACATCATTAATACCGAATTGCCTTTT
ATTGCTTTAGGAAATGCTCTTTGGGGAAGACATGAACTCTATCAAATAACGGAATTAAAGGAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9Q7E7G6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Haemophilus influenzae 86-028NP

40.467

98.467

0.398
  comA Haemophilus influenzae Rd KW20

39.3

98.467

0.387