Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EO946_RS06175 Genome accession   NZ_CP034943
Coordinates   1198197..1198853 (+) Length   218 a.a.
NCBI ID   WP_003224603.1    Uniprot ID   -
Organism   Bacillus spizizenii ATCC 6633 = JCM 2499 strain ATCC 6633     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1193197..1203853
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EO946_RS06145 (EO946_06145) oppF 1193653..1194570 (+) 918 WP_003224591.1 oligopeptide ABC transporter ATP-binding protein OppF -
  EO946_RS06150 (EO946_06150) - 1194676..1195890 (+) 1215 WP_079996334.1 MFS transporter -
  EO946_RS06155 (EO946_06155) - 1196068..1196646 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  EO946_RS06160 (EO946_06160) spx 1196827..1197222 (+) 396 WP_003224599.1 transcriptional regulator Spx -
  EO946_RS06165 (EO946_06165) - 1197265..1197921 (-) 657 WP_003224601.1 TerC family protein -
  EO946_RS06170 (EO946_06170) - 1198105..1198230 (+) 126 WP_120698858.1 hypothetical protein -
  EO946_RS06175 (EO946_06175) mecA 1198197..1198853 (+) 657 WP_003224603.1 adaptor protein MecA Regulator
  EO946_RS06180 (EO946_06180) - 1198848..1198969 (-) 122 Protein_1148 hypothetical protein -
  EO946_RS06185 (EO946_06185) coiA 1199013..1200164 (+) 1152 WP_003224605.1 competence protein CoiA Machinery gene
  EO946_RS06190 (EO946_06190) pepF 1200394..1202223 (+) 1830 WP_171017002.1 oligoendopeptidase F -
  EO946_RS06195 (EO946_06195) - 1202261..1202428 (-) 168 WP_019713977.1 hypothetical protein -
  EO946_RS06205 (EO946_06205) spxH 1202742..1203641 (-) 900 WP_003224611.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25777.67 Da        Isoelectric Point: 4.0970

>NTDB_id=333568 EO946_RS06175 WP_003224603.1 1198197..1198853(+) (mecA) [Bacillus spizizenii ATCC 6633 = JCM 2499 strain ATCC 6633]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCDMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=333568 EO946_RS06175 WP_003224603.1 1198197..1198853(+) (mecA) [Bacillus spizizenii ATCC 6633 = JCM 2499 strain ATCC 6633]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAGGAAGAGGAAT
TTGCTGTGGAAGGCCCTCTTTGGATTCAAGTTCAGGCACTCGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGGTTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCGATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991

Multiple sequence alignment