Detailed information NTG0333369

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: FWK43_RS07970
• Genome accession: NZ_CP042983
• Coordinates: 1746557..1747801 (+)
• Length: 414 a.a.
• NCBI ID: WP_075293630.1
• Uniprot ID: A0A9Q7E5Q0
• Organism: Histophilus somni strain UOC-KLM-ATR-01
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1741557..1752801

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FWK43_RS07955 (FWK43_07955)	pilB	1742802..1744193 (-)	1392	WP_101812545.1	GspE/PulE family protein	Machinery gene
FWK43_RS07960 (FWK43_07960)	tig	1744576..1745874 (+)	1299	WP_011609585.1	trigger factor	-
FWK43_RS07965 (FWK43_07965)	clpP	1745960..1746541 (+)	582	WP_012341086.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
FWK43_RS07970 (FWK43_07970)	clpX	1746557..1747801 (+)	1245	WP_075293630.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
FWK43_RS07975 (FWK43_07975)	ilvD	1748200..1750035 (-)	1836	WP_132995301.1	dihydroxy-acid dehydratase	-
FWK43_RS07980 (FWK43_07980)	-	1750208..1751758 (-)	1551	WP_132995303.1	exopolyphosphatase	-

Sequence

Protein

• Length: 414 a.a.
• Molecular weight: 46039.80 Da
• Isoelectric Point: 4.5662

>NTDB_id=333369 FWK43_RS07970 WP_075293630.1 1746557..1747801(+) (clpX) [Histophilus somni strain UOC-KLM-ATR-01]
MTKEKELHCSFCGKEQKEVDKLIAGTSGYICNECIELCHDMLANADDIEEIDEEFQEEEPKLPTPHEIRAHLDDYVIGQD
YAKKVLAVAVYNHYKRLRSEKNTSEVELGKSNILLIGPTGSGKTLLAQTLARMLNVPFAMADATTLTEAGYVGEDVENVL
QKLLQNCDYDIEKAQQGIIYIDEIDKITRKSENPSITRDVSGEGVQQALLKLVEGTVASIPPQGGRKHPQQEMLRVDTSK
ILFICGGAFAGLDKIIEKRTNTGGKGIGFGADVRIDEEKVSLTELFKQVEPDDLMKFGLIPEFIGRLPVIAPLSELDEEA
LVKILTEPKNALTKQYQVLFSLENIELEFTQEALIAMAKKALARKTGARGLRSIVETLLLDTMYDLPSIENLQKVIVEEE
TVTENKVPVLKFNS

Nucleotide

• Length: 1245 bp

>NTDB_id=333369 FWK43_RS07970 WP_075293630.1 1746557..1747801(+) (clpX) [Histophilus somni strain UOC-KLM-ATR-01]
ATGACAAAAGAAAAAGAATTACATTGCTCTTTTTGTGGTAAGGAACAAAAAGAAGTAGATAAATTAATTGCAGGCACATC
CGGTTATATTTGTAATGAGTGTATTGAATTATGTCATGACATGTTAGCTAATGCGGATGACATCGAAGAAATTGATGAAG
AATTTCAAGAGGAAGAGCCTAAATTACCGACACCACATGAAATTCGTGCACATTTAGATGATTATGTCATAGGCCAAGAT
TATGCTAAAAAAGTATTAGCTGTGGCGGTGTATAATCATTATAAACGTTTACGTAGCGAAAAAAATACTTCTGAGGTTGA
ATTGGGCAAAAGTAATATTTTGCTTATCGGCCCGACAGGCAGTGGCAAGACTTTATTGGCACAAACGTTAGCTCGTATGC
TCAATGTTCCCTTTGCAATGGCAGATGCAACAACTTTAACTGAAGCGGGATATGTTGGTGAAGATGTTGAAAATGTCTTG
CAAAAATTATTACAAAATTGTGATTATGATATAGAGAAAGCTCAACAAGGTATTATCTATATTGATGAAATTGATAAGAT
TACACGTAAGTCTGAAAATCCTTCTATTACTCGTGATGTATCAGGCGAAGGTGTGCAGCAGGCTTTACTAAAATTAGTTG
AAGGAACGGTAGCTTCTATTCCTCCACAAGGCGGACGAAAGCATCCTCAACAAGAAATGTTGCGTGTGGACACCTCTAAG
ATTTTATTTATTTGTGGCGGTGCTTTTGCCGGTTTAGATAAAATTATTGAGAAAAGAACGAATACCGGTGGCAAAGGTAT
TGGTTTTGGTGCTGATGTTCGTATTGATGAAGAGAAAGTCAGTTTAACCGAATTATTTAAGCAAGTTGAACCTGATGATT
TAATGAAATTTGGCTTAATACCGGAGTTTATCGGTCGTTTACCTGTTATCGCACCTTTAAGCGAACTGGATGAGGAGGCT
TTGGTAAAAATTTTAACTGAGCCGAAAAATGCCCTAACTAAGCAATATCAAGTTTTATTCAGCTTAGAAAATATTGAATT
AGAATTTACCCAAGAAGCATTGATTGCAATGGCGAAAAAAGCACTAGCTCGTAAAACAGGTGCCAGAGGTTTGCGATCTA
TTGTTGAAACCCTATTGCTTGATACTATGTATGATCTCCCTTCTATTGAAAACTTACAGAAAGTTATAGTGGAAGAAGAA
ACAGTCACCGAAAATAAAGTGCCAGTATTGAAGTTCAATAGTTAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (316-393)

• ClpX C4-type zinc finger (zf-C4_ClpX) (7-43)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-310)

3D structure

• AlphaFold DB: A0A9Q7E5Q0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.135	100	0.594
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	54.321	97.826	0.531